下颌后牙区萎缩的牙槽骨牵张成骨与嵌体植骨术：一项前瞻性研究。
Alveolar distraction osteogenesis versus inlay bone grafting in posterior mandibular atrophy: a prospective study.
作者信息
Bianchi Alberto, Felice Pietro, Lizio Giuseppe, Marchetti Claudio
机构信息
Postgraduate School of Maxillofacial Surgery, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Mar;105(3):282-92. doi: 10.1016/j.tripleo.2007.07.009.
OBJECTIVE
The objective of this study was to compare bone gain, implant survival, implant success, bone resorption, and complication rate in groups of patients who underwent distraction osteogenesis (DO) and inlay bone grafting (Inlay) for preprosthetic issues in the atrophic posterior mandible.
STUDY DESIGN
Twelve surgical sites were randomly assigned to 2 treatment groups: group A: DO and group B: Inlay. After 3 to 4 months, 16 fixtures in the DO group and 21 in the Inlay group were placed for fixed prosthetic rehabilitation. The median follow-up was 26 months.
RESULTS
The median bone gain was 10 versus 5.8 mm (DO versus Inlay, P = .003); the median bone resorption was 1.4 mm versus 0.9 mm (DO versus Inlay, P = .088). The implant survival rate was 100% for each group, while the implant success rate was 93.7% (DO) versus 95.2% (Inlay) (P > .05). The complication rate was 60% for DO and 14.3% for Inlay (P < .05).
CONCLUSION
DO obtained more vertical bone gain than Inlay, but was more prone to complications in the pre-implantology phase. The implant results in each group were comparable to those in native alveolar bone.
目的
本研究的目的是比较接受牵张成骨术（DO）和嵌体植骨术（Inlay）治疗萎缩性下颌后牙区修复前问题的患者组在骨增量、种植体存留率、种植体成功率、骨吸收和并发症发生率方面的差异。
研究设计
12个手术部位被随机分为2个治疗组：A组：DO组；B组：Inlay组。3至4个月后，DO组植入16颗种植体，Inlay组植入21颗种植体，进行固定义齿修复。中位随访时间为26个月。
结果
中位骨增量分别为10 mm和5.8 mm（DO组与Inlay组，P = .003）；中位骨吸收分别为1.4 mm和0.9 mm（DO组与Inlay组，P = .088）。每组种植体存留率均为100%，而种植体成功率分别为93.7%（DO组）和95.2%（Inlay组）（P > .05）。DO组并发症发生率为60%，Inlay组为14.3%（P < .05）。
结论
DO组比Inlay组获得更多的垂直骨增量，但在种植前阶段更容易出现并发症。每组的种植结果与天然牙槽骨的结果相当。
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