Ema Tadashi, Tanida Daisuke, Matsukawa Tatsuya, Sakai Takashi
Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University, Tsushima, Okayama 700-8530, Japan.
Chem Commun (Camb). 2008 Feb 28(8):957-9. doi: 10.1039/b718763g. Epub 2008 Jan 22.
Trifunctional organocatalysts and mimicking the active site of serine hydrolases showed high catalytic activity with up to a 3,700,000-fold acceleration for the acyl-transfer reactions from vinyl trifluoroacetate to alcohol.
三功能有机催化剂以及对丝氨酸水解酶活性位点的模拟显示出高催化活性,对于从三氟乙酸乙烯酯到醇的酰基转移反应,加速倍数高达370万倍。