Rapid lipid enrichment in omega3 fatty acids: cause-to-effect relationships.

The bolus intravenous administration of a novel medium-chain triglyceride:fish oil emulsion to second generation rats depleted in long-chain polyunsaturated omega3 fatty acids was recently found to enrich within 60 min the content of both plasma and liver lipids in such omega3 fatty acids, this coinciding with correction of the perturbation in liver triglyceride fatty acid content and profile otherwise prevailing in these rats. The present report draws attention to cause-to-effect relationships between changes in liver phospholipid and triglyceride fatty acid content and/or pattern operative under these experimental conditions.