Kulkas A, Rauhala E, Huupponen E, Virkkala J, Tenhunen M, Saastamoinen A, Himanen S-L
Department of Clinical Neurophysiology, Medical Imaging Centre, Pirkanmaa Hospital District, Tampere, Finland.
Med Biol Eng Comput. 2008 Apr;46(4):315-21. doi: 10.1007/s11517-008-0317-z. Epub 2008 Feb 21.
The objective of the present work was to develop automated methods for the compressed tracheal breathing sound analysis. Overnight tracheal breathing sound was recorded from ten apnoea patients. From each patient, three different types of tracheal sound deflection pattern, each of 10 min duration, were visually scored, viewing the compressed tracheal sound curve. Among them, high deflection patterns are of special interest due to the possible correlation with apnoea-hypopnoea sequences. Three methods were developed to detect patterns with high deflection, utilizing nonlinear filtering in local characterization of tracheal sounds. Method one comprises of local signal maximum, the second method of its local range, and the third of its relative range. The three methods provided 80% sensitivity with 57, 91 and 93% specificity, respectively. Method three provided an amplitude-independent approach. The nonlinear filtering based methods developed here offer effective means for analysing tracheal sounds of sleep-disordered breathing.
本研究的目的是开发用于压缩气管呼吸音分析的自动化方法。记录了10名呼吸暂停患者夜间的气管呼吸音。从每位患者的压缩气管音曲线中,目视评分三种不同类型的气管音偏转模式,每种持续10分钟。其中,高偏转模式因可能与呼吸暂停-低通气序列相关而特别受关注。开发了三种方法来检测高偏转模式,利用非线性滤波对气管音进行局部特征化。方法一包括局部信号最大值,方法二包括局部范围,方法三包括相对范围。这三种方法的灵敏度分别为80%,特异性分别为57%、91%和93%。方法三提供了一种与幅度无关的方法。这里开发的基于非线性滤波的方法为分析睡眠呼吸障碍的气管音提供了有效的手段。