Arnold Paul, Boswell Scott, McMahon Joan
Department of Neurosurgery, University of Kansas Medical Center, Kansas City, KS 66106, USA.
Surg Neurol. 2008 Oct;70(4):390-7. doi: 10.1016/j.surneu.2007.07.034. Epub 2008 Mar 4.
Anterior discectomy and fusion have been used for over 50 years in the treatment of degenerative disease of the cervical spine. However, as these procedures become more common, the long-term consequences are becoming more evident. One such consequence is degeneration of an adjacent segment, which can occur in up to 17% of patients undergoing cervical fusion. A threaded interbody fusion cage has often been used in a primary degenerative disorder of the cervical spine. However, there have been no studies in which these cages have been used in adjacent segments after previous cervical fusion. This is a retrospective review of 7 patients to determine the fusion rate, operative utility, and clinical outcomes using a threaded fusion cage construct in the treatment of cervical adjacent segment degeneration.
A standard low-profile interbody fusion cage was implanted after standard discectomy and local vertebral body bone graft in 7 patients with documented radiographic adjacent segment degeneration and clinical disease after anterior cervical fusion. Each patient underwent clinical and radiographic evaluation, and all 7 patients demonstrated signs of radiculopathy and/or myelopathy as well as radiographic signs of degeneration referable to a motion segment adjacent to previous cervical arthrodesis. These evaluations were repeated postoperatively. Patients were also asked to fill a preoperative and postoperative VAS, NDI, Prolo Economic-Functional Rating System, and CNDS for evaluation of outcome.
Each procedure was performed without complication. The mean VAS pain scale decreased 58% as a result of the surgery. The CNDS improved in all patients by an average of 42%. The NDI improved in all patients, with an average increase of 42%. The Prolo Economic-Function Status showed that 4 patients had an excellent outcome and 3 patients had a good outcome. There was no incidence of pseudoarthrosis in any procedure at the 24-month follow-up.
These preliminary results support the use of threaded interbody cages in adjacent segment degeneration of the cervical spine after previous anterior cervical fusion. Pain and functional scores improved in all cases. This technique should be among the possibilities for surgical treatment of degeneration of adjacent segments in patients with previous cervical spinal fusion.
前路椎间盘切除融合术用于治疗颈椎退行性疾病已有50多年历史。然而,随着这些手术越来越普遍,其长期后果也越来越明显。其中一个后果就是相邻节段退变,在接受颈椎融合术的患者中发生率高达17%。螺纹椎间融合器常用于颈椎原发性退行性疾病。然而,此前尚无研究将这些融合器用于既往颈椎融合术后的相邻节段。本文对7例患者进行回顾性研究,以确定使用螺纹融合器结构治疗颈椎相邻节段退变的融合率、手术效用及临床疗效。
对7例有影像学证实的颈椎前路融合术后相邻节段退变及临床疾病的患者,在标准椎间盘切除及局部椎体植骨后植入标准的低轮廓椎间融合器。每位患者均接受临床及影像学评估,所有7例患者均表现出神经根病和/或脊髓病体征以及与既往颈椎融合相邻运动节段的退变影像学表现。术后重复这些评估。还要求患者填写术前及术后的视觉模拟评分(VAS)、颈功能障碍指数(NDI)、普罗洛经济功能评分系统及颈椎功能障碍评分(CNDS)以评估疗效。
每例手术均无并发症发生。手术使VAS疼痛评分平均降低58%。所有患者的CNDS平均改善42%。所有患者的NDI均有改善,平均提高42%。普罗洛经济功能状态显示4例患者疗效极佳,3例患者疗效良好。在24个月随访时,所有手术均未发生假关节形成。
这些初步结果支持在既往颈椎前路融合术后的颈椎相邻节段退变中使用螺纹椎间融合器。所有病例的疼痛及功能评分均有改善。该技术应成为既往颈椎融合患者相邻节段退变手术治疗的选择之一。