Takamura Yoshihiro, Tomomatsu Takeshi, Matsumura Takehiro, Arimura Shogo, Gozawa Makoto, Takihara Yuji, Inatani Masaru
Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Eiheiji-cho, Yoshida, Fukui, 910-1193, Japan.
Jpn J Ophthalmol. 2015 Nov;59(6):394-400. doi: 10.1007/s10384-015-0406-0. Epub 2015 Aug 29.
To evaluate the correlation between central retinal thickness (CRT) after vitreous surgery and final visual outcome in eyes with idiopathic macular holes (MH).
A prospective analysis was performed of patients who had undergone surgical treatment for MH. Best-corrected visual acuity (BCVA) and optical coherence tomography (OCT) parameters including CRT, minimum and base diameters of the MHs were analyzed pre- and postoperatively. The relationships between final visual outcome and the OCT parameters were examined by single and multiple regression analysis.
Forty-one MHs cases were successfully closed postoperatively. BCVA gradually improved, and CRT decreased during the observation period following MH surgery. There were significant positive correlations between CRT at 1 month and visual acuity at 12 months after vitreous surgery (P < 0.0001). MH diameter was positively correlated with CRT at 1 month after surgery and negatively with postoperative visual acuity.
CRT at 1 month after MH surgery was related to preoperative MH diameter and visual acuity at 12 months postoperatively. Our data suggest that the increased CRT at the early postoperative period may result in better visual prognosis.
评估特发性黄斑裂孔（MH）患者玻璃体切除术后视网膜中央厚度（CRT）与最终视力结果之间的相关性。
对接受MH手术治疗的患者进行前瞻性分析。分析术前和术后的最佳矫正视力（BCVA）以及光学相干断层扫描（OCT）参数，包括CRT、MH的最小直径和基底直径。通过单因素和多因素回归分析检查最终视力结果与OCT参数之间的关系。
41例MH病例术后成功闭合。在MH手术后的观察期内，BCVA逐渐改善，CRT降低。玻璃体切除术后1个月时的CRT与术后12个月时的视力之间存在显著正相关（P < 0.0001）。MH直径与术后1个月时的CRT呈正相关，与术后视力呈负相关。
MH手术后1个月时的CRT与术前MH直径和术后12个月时的视力有关。我们的数据表明，术后早期CRT增加可能导致更好的视力预后。
