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犬类患者的抗体介导性视网膜病变:机制、诊断及治疗方式

Antibody-mediated retinopathies in canine patients: mechanism, diagnosis, and treatment modalities.

作者信息

Grozdanic Sinisa D, Harper Matthew M, Kecova Helga

机构信息

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2008 Mar;38(2):361-87, vii. doi: 10.1016/j.cvsm.2007.12.003.

Abstract

Antibody-mediated retinopathies may be widely present among the canine population. Early diagnosis and appropriate treatment are essential for visual preservation and reversal of blindness in these patients. The principal purpose of this review is to describe the mechanistic basis, clinical signs, diagnostic methods, and treatment options for retinal diseases causing sudden onset of blindness with absence of typical signs of intraocular inflammation or retinal degeneration-sudden acquired retinal degeneration syndrome and immune-mediated retinitis.

摘要

抗体介导的视网膜病变可能广泛存在于犬类群体中。早期诊断和适当治疗对于这些患者的视力保护和失明逆转至关重要。本综述的主要目的是描述导致突然失明且无眼内炎症或视网膜变性典型体征的视网膜疾病——突然获得性视网膜变性综合征和免疫介导性视网膜炎的发病机制、临床症状、诊断方法和治疗选择。

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