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同时存在的结核分枝杆菌、肺炎克雷伯菌和白色念珠菌感染于结肠癌肝转移中。

Concurrent M. tuberculosis, Klebsiella pneumoniae, and Candida albicans infection in liver metastasis of bowel carcinoma.

作者信息

Rafailidis P I, Kapaskelis A, Christodoulou C, Galani E, Falagas M E

机构信息

Alfa Institute of Biomedical Sciences (AIBS), Athens, Greece.

出版信息

Eur J Clin Microbiol Infect Dis. 2008 Aug;27(8):753-5. doi: 10.1007/s10096-008-0488-4. Epub 2008 Feb 26.

Abstract

We describe the case of a 62-year-old patient with fever and abdominal pain of the right upper quadrant with a known history of adenocarcinoma of the colon and presence of hepatic metastases. One of the liver lesions underwent aspiration, and pus was sent for microbiological testing. Cultures of the pus were positive for Klebsiella pneumoniae and Candida albicans and polymerase chain reaction for Mycobacterium tuberculosis was concurrently positive; the patient received treatment for all three pathogens and improved clinically. One may consider searching not only for the usual pathogens of liver abscesses (gram-negative bacteria, anaerobic bacteria and gram-positive bacteria), but in special cases might consider pursuing a more detailed search for coexistence of fungi and mycobacteria in patients with cancer.

摘要

我们描述了一名62岁患者的病例,该患者有发热及右上腹疼痛症状,有结肠癌病史且存在肝转移。对其中一个肝脏病灶进行了穿刺抽吸,抽出的脓液送去做微生物检测。脓液培养结果显示肺炎克雷伯菌和白色念珠菌呈阳性,同时结核分枝杆菌聚合酶链反应也呈阳性;患者针对这三种病原体接受了治疗,临床症状有所改善。人们不仅应考虑查找肝脓肿常见的病原体(革兰氏阴性菌、厌氧菌和革兰氏阳性菌),在特殊情况下还可能需要更详细地查找癌症患者中真菌和分枝杆菌的共存情况。

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