Wikström J, Hansen T, Johansson L, Lind L, Ahlström H
Department of Radiology and Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden.
Acta Radiol. 2008 Mar;49(2):143-9. doi: 10.1080/02841850701732957.
Whole-body magnetic resonance angiography (WBMRA) permits noninvasive vascular assessment, which can be utilized in epidemiological studies.
To assess the relation between a low ankle brachial index (ABI) and high-grade stenoses in the pelvic and leg arteries in the elderly.
WBMRA was performed in a population sample of 306 subjects aged 70 years. The arteries below the aortic bifurcation were graded after the most severe stenosis according to one of three grades: 0-49% stenosis, 50-99% stenosis, or occlusion. ABI was calculated for each side.
There were assessable WBMRA and ABI examinations in 268 (right side), 265 (left side), and 258 cases (both sides). At least one > or =50% stenosis was found in 19% (right side), 23% (left side), and 28% (on at least one side) of the cases. The corresponding prevalences for ABI <0.9 were 4.5%, 4.2%, and 6.6%. An ABI cut-off value of 0.9 resulted in a sensitivity, specificity, and positive and negative predictive value of 20%, 99%, 83%, and 84% on the right side, and 15%, 99%, 82%, and 80% on the left side, respectively, for the presence of a > or =50% stenosis in the pelvic or leg arteries.
An ABI <0.9 underestimates the prevalence of peripheral arterial occlusive disease in the general elderly population.
全身磁共振血管造影（WBMRA）可进行无创血管评估，可用于流行病学研究。
评估老年人群中低踝臂指数（ABI）与盆腔及腿部动脉重度狭窄之间的关系。
对306名70岁的人群样本进行WBMRA检查。根据最严重狭窄程度将主动脉分叉以下动脉分为三个等级之一：0 - 49%狭窄、50 - 99%狭窄或闭塞。计算每侧的ABI。
268例（右侧）、265例（左侧）和258例（双侧）可进行WBMRA和ABI检查。19%（右侧）、23%（左侧）和28%（至少一侧）的病例发现至少一处≥50%的狭窄。ABI<0.9的相应患病率分别为4.5%、4.2%和6.6%。对于盆腔或腿部动脉存在≥50%的狭窄，ABI临界值为0.9时，右侧的敏感性、特异性、阳性预测值和阴性预测值分别为20%、99%、83%和84%，左侧分别为15%、99%、82%和80%。
ABI<0.9低估了一般老年人群外周动脉闭塞性疾病的患病率。
