Lü Quanjun, Wang Huali, Hu Tongyu, Zhu Mingjun
College of Public Health, Zhengzhou University, Zhengzhou 450052, China.
Wei Sheng Yan Jiu. 2007 Nov;36(6):719-21.
To study the changes of vitamin nutritional status of residents in a high-risk area of esophageal cancer.
8 towns where nutrition survey had been done were selected, 2 villages were randomly selected from each town and 30 families were randomly selected per village. The blood and 4h burden urine samples were collected from subjects. The serum vitamin A, blood total ascorbic acid and glutathione reductase activition coefficient (AC) in red blood cell were determinde by using of trifluoroacetic acid colorimetry, 2, 4-dinitrophenylhydrazine colorimetric method and Sauberlich method respectively. The contents of vitamin B2 , reduction ascorbic acid and total ascorbic acid in 4h burden urine were measured by using of fluorescent pectrophotometry,2,6-Dichloro-N-(4-hydroxyphenyl)-1,4-benzoquinoneimine titrimetric method and 2,4-dinitrophenylhydrazine colorimetric method respectively. The results were analyzed and compared with those of in 1980, 1983 and 1984. The t-test or chi2-test was carried out.
The level of serum retinal in residents living in Ren cun, Dongyao and Hejian is significantly higher than that of in 1982 (P < 0.01). The level of vitamin B2 in 4h burden urine in residents living in Yaocun, Rencun and Heshun are significantly higher than that of in 1982 or 1984 (P < 0.01). The number of ribflavin deficiency of population living in Dongyao, Hejian, Yaocun and Rencun are significantly lower than that of in 1982 or 1983 (P < 0.01) according to the content of 4h burden urine and glutathione reductase activation coefficient (AC) in red blood cell; the number of vitamin C deficiency of population living in Dongyao, Hejian,Yao cun, Ren cun and Heshun are significantly lower than that of in 1982 or 1983 (P < 0.01) according to blood total ascorbic acid and the ascorbic acid content of 4h-burden urine and.
Vitamin nutritional status of residents in a high-risk area of esophageal cancer have been improved.
研究食管癌高发区居民维生素营养状况的变化。
选取已进行营养调查的8个镇，每个镇随机抽取2个村，每个村随机抽取30户家庭。采集受试者的血液和4小时负荷尿样。分别采用三氟乙酸比色法、2,4-二硝基苯肼比色法和索伯利希法测定血清维生素A、血液总抗坏血酸和红细胞谷胱甘肽还原酶激活系数（AC）。采用荧光分光光度法、2,6-二氯-N-（4-羟基苯基）-1,4-苯醌亚胺滴定法和2,4-二硝基苯肼比色法分别测定4小时负荷尿中维生素B2、还原型抗坏血酸和总抗坏血酸的含量。对结果进行分析，并与1980年、1983年和1984年的结果进行比较。进行t检验或卡方检验。
任村、东姚和河间居民的血清视黄醇水平显著高于1982年（P<0.01）。瑶村、任村和顺村居民4小时负荷尿中维生素B2水平显著高于1982年或1984年（P<0.01）。根据4小时负荷尿含量和红细胞谷胱甘肽还原酶激活系数（AC），东姚、河间、瑶村和任村人群核黄素缺乏人数显著低于1982年或1983年（P<0.01）；根据血液总抗坏血酸、4小时负荷尿抗坏血酸含量，东姚、河间、瑶村、任村和顺村人群维生素C缺乏人数显著低于1982年或1983年（P<0.01）。
食管癌高发区居民的维生素营养状况有所改善。
