Yang Z, Zhao W, Zhang X, Mu R, Zhai Y, Kong L, Chen C
Chinese Center for Disease Control and Prevention, Beijing, China.
Obes Rev. 2008 Mar;9 Suppl 1:95-9. doi: 10.1111/j.1467-789X.2007.00447.x.
The objectives of the present study are (i) To examine the association between fetal nutritional status and overweight and obesity in adulthood and (ii) to provide the evidence for formulating a strategy to prevent low birth weight. With data from the 2002 Nationwide Nutrition and Health Survey, the body mass indexes (BMIs) of rural residents born during the famine years of 1959, 1960, 1961 were compared with those born in 1964. The health consequence of famine on the adulthood BMI was evident in women; the mean BMIs of the women were significantly higher in the three famine groups than that in the control group born in 1964 (P < 0.01). After adjustment for regional differences within China, the prevalences of overweight in women were significantly higher in the three famine groups (P < 0.01) and of obesity in the 1959 and 1960 groups. (P < 0.01). Such differences were not found in men. The higher risks of overweight and obesity in women were caused by malnutrition in fetal life. A strategy for preventing low birth weight should be formulated by the government to prevent chronic disease in adulthood.
（i）研究胎儿营养状况与成年期超重和肥胖之间的关联；（ii）为制定预防低出生体重的策略提供依据。利用2002年全国营养与健康调查的数据，将1959年、1960年、1961年饥荒年份出生的农村居民的体重指数（BMI）与1964年出生的农村居民的体重指数进行比较。饥荒对成年期BMI的健康影响在女性中很明显；三个饥荒组女性的平均BMI显著高于1964年出生的对照组女性（P<0.01）。在中国区域差异校正后，三个饥荒组女性的超重患病率显著更高（P<0.01），1959年和1960年组女性的肥胖患病率显著更高（P<0.01）。在男性中未发现此类差异。女性超重和肥胖风险较高是由胎儿期营养不良所致。政府应制定预防低出生体重的策略，以预防成年期慢性病。
