Grotta James C, Jacobs Thomas P, Koroshetz Walter J, Moskowitz Michael A
Department of Neurology, University of Texas-Houston Medical School, 6431 Fannin St, Houston TX 77080, USA.
Stroke. 2008 Apr;39(4):1364-70. doi: 10.1161/STROKEAHA.107.510776. Epub 2008 Feb 28.
The Stroke Program Review Group (SPRG) met for the first time in 2001 to identify and prioritize scientific needs and opportunities in stroke, and to consider strategies to address them. Out of this meeting came a set of scientific and resource recommendations (http://www.ninds.nih.gov/find_people/groups/stroke_prg/index.htm) including the recommendation to review progress after 5 years. In September 2006, the NINDS convened a second SPRG of prominent scientists, clinicians, industry leaders, and patient advocates to discuss progress since the first SPRG and to examine new opportunities in light of more recent advances. The report of the second SPRG meeting is found at http://www.ninds.nih.gov/find_people/groups/stroke_prg/09_2006_stroke_prg_report.htm. In this brief interim report, we list and summarize progress in each of the investigational domains outlined in the SPRG with an emphasis on those advances directly resulting from NINDS-funded research. Also listed are the top 2 or 3 research priorities for the next 5-year cycle for each investigational theme. What emerges from the first 2 reports is a clear set of priorities that have since been complemented by exciting advances that are likely to be the focus of a follow-up report from the next SPRG in 2010.
中风项目审查小组(SPRG)于2001年首次召开会议,以确定中风领域的科学需求和机会并排出优先顺序,并考虑应对这些需求和机会的策略。此次会议产生了一系列科学和资源建议(http://www.ninds.nih.gov/find_people/groups/stroke_prg/index.htm),包括5年后审查进展情况的建议。2006年9月,美国国立神经疾病与中风研究所(NINDS)召集了由杰出科学家、临床医生、行业领袖和患者权益倡导者组成的第二届SPRG会议,讨论自第一届SPRG会议以来的进展情况,并根据最新进展研究新的机会。第二届SPRG会议的报告可在http://www.ninds.nih.gov/find_people/groups/stroke_prg/09_2006_stroke_prg_report.htm上查阅。在这份简短的中期报告中,我们列出并总结了SPRG概述的每个研究领域的进展情况,重点是国立神经疾病与中风研究所资助研究直接产生的那些进展。还列出了每个研究主题在未来5年周期中的两到三个首要研究重点。前两份报告明确了一系列优先事项,此后又有令人振奋的进展,这些进展可能会成为2010年下一届SPRG后续报告的重点。