Akiyama H, Yamada T, Kawamata T, McGeer P L
Kinsmen Laboratory of Neurological Research, Department of Psychiatry, University of British Columbia, Vancouver, Canada.
Brain Res. 1991 May 10;548(1-2):349-52. doi: 10.1016/0006-8993(91)91148-t.
Amyloid P component (AP) was detected in a number of lesions in human brain associated with chronic degenerative disease. These lesions included diffuse and consolidated amyloid deposits, cerebral amyloid angiopathy, neurofibrillary tangles, neuropil threads and complement activated oligodendroglia. The staining for AP generally paralleled that for complement proteins C4d and C3d, suggesting that AP may serve as an adjuvant for phagocytosis.
在人类大脑中与慢性退行性疾病相关的一些病变中检测到了淀粉样蛋白P成分（AP）。这些病变包括弥漫性和致密性淀粉样沉积物、脑淀粉样血管病、神经原纤维缠结、神经毡丝和补体激活的少突胶质细胞。AP的染色通常与补体蛋白C4d和C3d的染色平行，这表明AP可能作为吞噬作用的佐剂。
