Mattei Eugenio, Triventi Michele, Calcagnini Giovanni, Censi Federica, Kainz Wolfgang, Mendoza Gonzalo, Bassen Howard I, Bartolini Pietro
Dept. of Technologies and Health, Italian National Institute of Health, Roma, Italy.
Biomed Eng Online. 2008 Mar 3;7:11. doi: 10.1186/1475-925X-7-11.
MRI induced heating on PM leads is a very complex issue. The widely varying results described in literature suggest that there are many factors that influence the degree of heating and that not always are adequately addressed by existing testing methods.
We present a wide database of experimental measurements of the heating of metallic wires and PM leads in a 1.5 T RF coil. The aim of these measurements is to systematically quantify the contribution of some potential factors involved in the MRI induced heating: the length and the geometric structure of the lead; the implant location within the body and the lead path; the shape of the phantom used to simulate the human trunk and its relative position inside the RF coil.
We found that the several factors are the primary influence on heating at the tip. Closer locations of the leads to the edge of the phantom and to the edge of the coil produce maximum heating. The lead length is the other crucial factor, whereas the implant area does not seem to have a major role in the induced temperature increase. Also the lead structure and the geometry of the phantom revealed to be elements that can significantly modify the amount of heating.
Our findings highlight the factors that have significant effects on MRI induced heating of implanted wires and leads. These factors must be taken into account by those who plan to study or model MRI heating of implants. Also our data should help those who wish to develop guidelines for defining safe medical implants for MRI patients. In addition, our database of the entire set of measurements can help those who wish to validate their numerical models of implants that may be exposed to MRI systems.
MRI对心脏起搏器导线产生的加热是一个非常复杂的问题。文献中描述的结果差异很大,这表明有许多因素会影响加热程度,而现有测试方法并非总能充分解决这些因素。
我们展示了一个关于在1.5T射频线圈中金属丝和心脏起搏器导线加热的广泛实验测量数据库。这些测量的目的是系统地量化一些与MRI诱导加热相关的潜在因素的影响:导线的长度和几何结构;体内植入位置和导线路径;用于模拟人体躯干的模型形状及其在射频线圈内的相对位置。
我们发现有几个因素是尖端加热的主要影响因素。导线越靠近模型边缘和线圈边缘,产生的加热就越大。导线长度是另一个关键因素,而植入区域似乎对诱导温度升高没有主要作用。此外,导线结构和模型几何形状也显示出可显著改变加热量的因素。
我们的研究结果突出了对植入导线和电极的MRI诱导加热有显著影响的因素。计划研究或模拟植入物MRI加热的人员必须考虑这些因素。我们的数据也应该有助于那些希望制定MRI患者安全医疗植入物定义指南的人。此外,我们的整套测量数据库可以帮助那些希望验证其可能暴露于MRI系统的植入物数值模型的人。