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磁共振成像期间可生物降解骨科螺钉植入物的射频感应加热

Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging.

作者信息

Espiritu Jonathan, Berangi Mostafa, Cwieka Hanna, Iskhakova Kamila, Kuehne Andre, Florian Wieland D C, Zeller-Plumhoff Berit, Niendorf Thoralf, Willumeit-Römer Regine, Seitz Jan-Marten

机构信息

Syntellix AG, Hannover, Germany.

MRI.TOOLS GmbH, Berlin, Germany.

出版信息

Bioact Mater. 2023 Jan 23;25:86-94. doi: 10.1016/j.bioactmat.2023.01.017. eCollection 2023 Jul.

Abstract

Magnesium (Mg)-based implants have re-emerged in orthopaedic surgery as an alternative to permanent implants. Literature reveals little information on how the degradation of biodegradable implants may introduce safety implications for patient follow-up using medical imaging. Magnetic resonance imaging (MRI) benefits post-surgery monitoring of bone healing and implantation sites. Previous studies demonstrated radiofrequency (RF) heating of permanent implants caused by electromagnetic fields used in MRI. Our investigation is the first to report the effect of the degradation layer on RF-induced heating of biodegradable orthopaedic implants. WE43 orthopaedic compression screws underwent degradation. Imaging techniques were applied to assess the corrosion process and the material composition of the degraded screws. Temperature measurements were performed to quantify implant heating with respect to the degradation layer. For comparison, a commercial titanium implant screw was used. Strongest RF induced heating was observed for non-degraded WE43 screw samples. Implant heating had shown to decrease with the formation of the degradation layer. No statistical differences were observed for heating of the non-degraded WE43 material and the titanium equivalent. The highest risk of implant RF heating is most pronounced for Mg-based screws prior to degradation. Amendment to industry standards for MRI safety assessment is warranted to include biodegradable materials.

摘要

镁(Mg)基植入物在骨科手术中重新出现,成为永久性植入物的替代选择。文献中关于可生物降解植入物的降解如何给使用医学成像进行患者随访带来安全隐患的信息很少。磁共振成像(MRI)有助于术后对骨愈合和植入部位进行监测。先前的研究表明,MRI中使用的电磁场会导致永久性植入物产生射频(RF)加热。我们的研究首次报告了降解层对可生物降解骨科植入物射频感应加热的影响。对WE43骨科加压螺钉进行了降解处理。应用成像技术评估降解螺钉的腐蚀过程和材料成分。进行温度测量以量化与降解层相关的植入物加热情况。为作比较,使用了一种商用钛植入螺钉。对于未降解的WE43螺钉样本,观察到最强的射频感应加热。随着降解层的形成,植入物加热已显示出减少。未降解的WE43材料和钛等效物的加热情况未观察到统计学差异。基于镁的螺钉在降解之前,植入物射频加热的最高风险最为明显。有必要修订MRI安全评估的行业标准,以纳入可生物降解材料。

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