Pharmacognosy and Phytochemistry Division, Faculty of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, India.
Evid Based Complement Alternat Med. 2008 Mar;5(1):91-4. doi: 10.1093/ecam/nem003.
Ancient literature mentions the use of a number of plants/preparations for fertility regulation. Some local contraceptive agents have also been described in Ayurvedic and Unani texts. Documented experiments or clinical data are, however, lacking. Therefore, the present study was undertaken to explore the antifertility and estrogenic activity of ethanolic extract of the roots of Hibiscus rosa-sinensis Linn. A strong anti-implantation (inhibition 100%) and uterotropic activity was observed at the dose level of 400 mg/kg body weight. Histological studies were carried out to confirm this effect.
古代文献提到了一些植物/制剂在生育调节方面的应用。一些局部避孕药也在印度阿育吠陀和尤那尼文本中有描述。然而,缺乏有记录的实验或临床数据。因此,进行了本项研究以探索木槿根的乙醇提取物的抗生育和雌激素活性。在 400 毫克/千克体重的剂量水平下,观察到强烈的抗着床(抑制 100%)和子宫营养活性。进行了组织学研究以证实这一效果。