Lundgren Tobias, Dahl JoAnne, Hayes Steven C
Department of Psychology, University of Uppsala, Trädgårdsgatan 20, P.O. Box 1225, 751 42 Uppsala, Sweden.
J Behav Med. 2008 Jun;31(3):225-35. doi: 10.1007/s10865-008-9151-x. Epub 2008 Mar 6.
The present study examined the mediators of change accounting for outcomes of a previously published study on acceptance and commitment therapy for the self-management of epilepsy and its life restricting impact. Conducted with 27 poor South Africans, a 9-h ACT protocol that included seizure management methods was shown to greatly reduce epileptic seizures and to increase quality of life over the next year as compared to an attention placebo control. A series of bootstrapped non-parametric multiple mediator tests showed that pre to follow-up changes in: seizures, quality of life, and well-being outcomes were mediated to a degree by ACT process measures of epilepsy-related acceptance or defusion, values attainment, persistence in the face of barriers, or their combination. The results of this study contribute to the understanding of the contextual conditioning mechanisms at work for those suffering from epilepsy and may show that helping people live vital lives may also help to reduce seizures.
本研究探讨了变化的中介因素，这些因素解释了先前发表的一项关于接受与承诺疗法对癫痫自我管理及其生活限制影响的研究结果。对27名贫穷的南非人进行的一项为期9小时的接受与承诺疗法方案（其中包括癫痫发作管理方法）显示，与注意力安慰剂对照组相比，该方案在接下来的一年里能大幅减少癫痫发作，并提高生活质量。一系列自抽样非参数多重中介测试表明，从基线到随访期间，癫痫发作、生活质量和幸福感结果的变化在一定程度上是由与癫痫相关的接受或解离、价值观实现、面对障碍时的坚持等接受与承诺疗法过程指标，或它们的组合所介导的。本研究结果有助于理解癫痫患者所涉及的情境调节机制，并且可能表明帮助人们过上有意义的生活也有助于减少癫痫发作。
