Postgate Aymer Jonathan, Burling David, Gupta Arun, Fitzpatrick Aine, Fraser Chris
Wolfson Unit for Endoscopy, St Mark's Hospital, Watford Road, London, HA1 3UJ, UK.
Dig Dis Sci. 2008 Oct;53(10):2732-8. doi: 10.1007/s10620-008-0210-5. Epub 2008 Mar 5.
The patency capsule may prevent capsule retention in high-risk patients. However data on its use in routine clinical practice is limited.
Patients referred to our institution between Feb-04 and Jan-07 were reviewed. The following data was collected: presenting symptoms; medical/surgical history; medication; radiology; patency/video capsule result; subsequent investigations; clinical outcomes.
373 patients were referred. In 315 (84%) 'low-risk' patients (no patency capsule): delayed transit occurred in three, with no cases of capsule retention. In 58 (16%) 'high risk' patients (patency capsule): asymptomatic retention occurred in eight, all with pathology despite normal prior barium studies in six; in four cases patency location was incorrectly assessed radiologically, leading to video capsule retention and surgery in one.
Most patients can safely undergo capsule endoscopy without a patency capsule. The patency capsule appears safe and is indicative of pathology when retained. Assessment of patency capsule location post ingestion can be difficult, and if barium radiology is equivocal a limited abdominal computed tomography (CT) scan is suggested.
通畅性胶囊可能会防止高危患者出现胶囊滞留情况。然而，关于其在常规临床实践中使用的数据有限。
对2004年2月至2007年1月转诊至我院的患者进行回顾性研究。收集了以下数据：临床表现；内科/外科病史；用药情况；放射学检查结果；通畅性/视频胶囊检查结果；后续检查；临床结局。
共转诊373例患者。在315例（84%）“低风险”患者（未使用通畅性胶囊）中，3例出现转运延迟，无胶囊滞留病例。在58例（16%）“高风险”患者（使用通畅性胶囊）中，8例出现无症状滞留，其中6例尽管之前钡剂检查正常但均有病变；4例通畅性胶囊位置经放射学检查评估错误，导致1例视频胶囊滞留并接受手术。
大多数患者在不使用通畅性胶囊的情况下可安全地进行胶囊内镜检查。通畅性胶囊似乎是安全的，滞留时提示有病变。摄入后评估通畅性胶囊位置可能困难，若钡剂放射学检查结果不明确，建议进行有限的腹部计算机断层扫描（CT）。
