Santamaría Rodrigo, Therón Roberto, Quintales Luis
Departamento de Informática y Automática, Pz. de Los Caídos S/N, 37008 Salamanca, Spain.
Bioinformatics. 2008 May 1;24(9):1212-3. doi: 10.1093/bioinformatics/btn076. Epub 2008 Mar 5.
BicOverlapper is a tool to visualize biclusters from gene-expression matrices in a way that helps to compare biclustering methods, to unravel trends and to highlight relevant genes and conditions. A visual approach can complement biological and statistical analysis and reduce the time spent by specialists interpreting the results of biclustering algorithms. The technique is based on a force-directed graph where biclusters are represented as flexible overlapped groups of genes and conditions.
The BicOverlapper software and supplementary material are available at http://vis.usal.es/bicoverlapper
双聚类重叠器是一种用于可视化基因表达矩阵中的双聚类的工具，它有助于比较双聚类方法、揭示趋势并突出相关基因和条件。可视化方法可以补充生物学和统计分析，并减少专家解释双聚类算法结果所花费的时间。该技术基于一种力导向图，其中双聚类被表示为基因和条件的灵活重叠组。
双聚类重叠器软件和补充材料可在http://vis.usal.es/bicoverlapper获取。
