Kappelman Michael D, Bousvaros Athos
Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA, USA.
Mol Nutr Food Res. 2008 Aug;52(8):867-74. doi: 10.1002/mnfr.200700156.
In approximately one-fourth of patients with Crohn's disease (CD) and ulcerative colitis (UC), disease onset occurs during childhood and adolescence. In addition to gastrointestinal and extraintestinal symptoms of inflammatory bowel disease (IBD), children with these conditions often experience one or more nutritional complications of their disease including growth failure, delayed puberty, osteoporosis, anemia, and micronutrient deficiencies. This article provides an overview of the epidemiology, pathophysiology, evaluation, and management of selected nutritional complications in pediatric IBD.
在大约四分之一的克罗恩病(CD)和溃疡性结肠炎(UC)患者中,疾病发作发生在儿童期和青少年期。除了炎症性肠病(IBD)的胃肠道和肠外症状外,患有这些疾病的儿童通常还会经历一种或多种疾病的营养并发症,包括生长发育迟缓、青春期延迟、骨质疏松、贫血和微量营养素缺乏。本文概述了儿童IBD中特定营养并发症的流行病学、病理生理学、评估和管理。