Tann Oliver R, Tulloh Robert M R, Hamilton Mark C K
Department of Clinical Radiology, Bristol Royal Infirmary, Marlborough St. Bristol, UK.
Cardiol Young. 2008 Jun;18(3):250-9. doi: 10.1017/S1047951108002060. Epub 2008 Mar 7.
Takayasu's disease is a rare chronic vasculitis of unknown aetiology. Initial symptoms and signs are non-specific, and a high index of suspicion is needed to make the correct diagnosis. The disease is associated with a high incidence of morbidity, and a significant risk of premature death. Serological tests have proved unreliable in distinguishing active from quiescent disease, with non-invasive imaging currently offering the best option for early diagnosis, and monitoring the response to treatment. In this review, we detail the epidemiology, pathophysiology, clinical features, imaging characteristics, and currently available treatments.
高安氏病是一种病因不明的罕见慢性血管炎。最初的症状和体征不具有特异性，需要高度怀疑才能做出正确诊断。该疾病发病率高，且有过早死亡的重大风险。血清学检测在区分疾病的活动期和静止期方面已被证明不可靠，目前非侵入性成像为早期诊断和监测治疗反应提供了最佳选择。在本综述中，我们详细介绍了其流行病学、病理生理学、临床特征、影像学特征以及目前可用的治疗方法。
