Division of Pediatric Rheumatology, Children's Hospital of Pittsburgh of UPMC, 4401 Penn Avenue, 15224, Pittsburgh, PA, USA.
Pediatr Rheumatol Online J. 2013 Feb 12;11(1):4. doi: 10.1186/1546-0096-11-4.
Takayasu's arteritis (TA) is a form of chronic vasculitis that typically occurs in young adult Asian females, but it can also present in younger patients not fitting this classic profile. In these cases, the sequelae are generally similar to those found in adults. The disease predominantly affects the aorta and its primary branches. However, the coronary arteries are also affected in up to 20% of cases, which may precipitate myocardial infarction. Imaging of the coronary arteries therefore becomes critically important in the evaluation of a patient with possible Takayasu's arteritis. We present a case of a pediatric patient with TA who had no symptoms of angina but who was found to have significant coronary artery involvement on diagnostic imaging. This necessitated tailoring of traditional management.
Takayasu 动脉炎(TA)是一种慢性血管炎,通常发生在年轻的成年亚裔女性中,但也可能发生在不符合这种典型特征的年轻患者中。在这些情况下,后遗症通常与成年人相似。该疾病主要影响主动脉及其主要分支。然而,冠状动脉在多达 20%的病例中也受到影响,这可能导致心肌梗死。因此,冠状动脉的影像学检查在评估可能患有 Takayasu 动脉炎的患者时变得至关重要。我们报告了一例儿科 TA 患者,该患者没有心绞痛症状,但在诊断性影像学检查中发现有明显的冠状动脉受累。这需要对传统治疗方法进行调整。