Pacor M L, Marchi G, Peroli P, Nicolis F, Cortina P, Lunardi C
Istituto di Patologia Medica, Università degli Studi di Verona.
Clin Ter. 1991 Jun 15;137(5):321-5.
Recently, a new immunoenzymatic test (Allergy Screen Profile, ASP) has been proposed for the simultaneous determination of IgE specific for five inhaled allergens (Dermatophagoides, animal dander, trees, grass pollen and Parietaria). For evaluation of this test we compared the results obtained in twenty-seven patients suffering from respiratory allergy with RAST with those obtained using the new test. In 84.3% of cases there was positive concordance between the two tests. The specificity of ASP ranged from 71.4% to 100% and the sensitivity from 76.9% to 95.2% for the different allergens examined. A good correlation between ASP and RAST was particularly evident for Dermatophagoides, animal dander and trees. Therefore, ASP appears to be a suitable test for the simultaneous determination of IgE specific for different allergens.
最近，一种新的免疫酶检测法（过敏筛查组合，ASP）被提出来用于同时测定针对五种吸入性变应原（尘螨、动物皮屑、树木、草花粉和墙草）的特异性IgE。为了评估该检测法，我们将27例患有呼吸道过敏的患者使用放射变应原吸附试验（RAST）得到的结果与使用这种新检测法得到的结果进行了比较。在84.3%的病例中，两种检测法结果呈阳性一致。对于所检测的不同变应原，ASP的特异性范围为71.4%至100%，敏感性范围为76.9%至95.2%。对于尘螨、动物皮屑和树木，ASP与RAST之间的良好相关性尤为明显。因此，ASP似乎是一种适用于同时测定针对不同变应原的特异性IgE的检测方法。
