Rosenow Felix, Hamer Hajo M, Knake Susanne
Interdisciplinary Epilepsy Center, University Hospital Giessen, Marburg, Germany.
Epilepsia. 2007;48 Suppl 8:82-4. doi: 10.1111/j.1528-1167.2007.01359.x.
Epidemiologic studies of status epilepticus (SE) depend on clear definitions of terms. Such a definition is available for convulsive generalized SE, but clear definitions of nonconvulsive SE (NCSE) are lacking. This as well as clinical difficulties to diagnose NCSE are one source of underascertainment. The minimal incidence of SE in the Caucasian population of industrialized countries is about 20/100,000/year. It depends on age, ethnic background and possibly gender. Case fatality rates lie between 1.9 and 40% depending on age, etiology and duration of the SE. Effective treatment can improve and focal SE itself may impair case fatality. Clearly increased rates of long term case fatality in patients with symptomatic SE suggest that these patients should be considered a population at high risk.
癫痫持续状态(SE)的流行病学研究依赖于术语的明确定义。惊厥性全身性SE已有这样的定义,但非惊厥性SE(NCSE)缺乏明确的定义。这以及诊断NCSE的临床困难是确诊不足的一个原因。工业化国家白种人群中SE的最低发病率约为每年20/10万。它取决于年龄、种族背景,可能还与性别有关。病死率在1.9%至40%之间,取决于年龄、病因和SE的持续时间。有效的治疗可改善病情,而局灶性SE本身可能会影响病死率。有症状SE患者的长期病死率明显升高,这表明这些患者应被视为高危人群。