Randolph Chris
Center for Allergy, Asthma, Immunology, 1389 West Main Street, Suite 205, Waterbury, CT 06708, USA.
Clin Rev Allergy Immunol. 2008 Apr;34(2):205-16. doi: 10.1007/s12016-007-8035-0.
This review will encompass definition, history, epidemiology, pathogenesis, diagnosis, and management of exercise -induced bronchospasm in the pediatric individual with and without known asthma. Exercise induced asthma is the conventional term for transient airway narrowing in a known asthma in association with strenuous exercise usually lasting 5-10 minutes with a decline in pulmonary function by at least 10%. Exercise induced asthma will be referred to as exercise induced bronchospasm in an asthmatic. Exercise-induced bronchospasm (EIB ) is the same phenomenon in an individual without known asthma. EIB can be seen in healthy individuals including children as well as defense recruits and competitive or elite athletes. The diagnosis with objective exercise challenge methods in conjunction with history is delineated. Management is characterized with pharmacotherapy and non pharmacotherapeutic measures for underlying asthma as well as exercise induced bronchospasm and inhalant allergy. Children can successfully participate in all sports if asthma is properly managed.
本综述将涵盖已知患有哮喘和未患哮喘的儿童运动诱发性支气管痉挛的定义、历史、流行病学、发病机制、诊断和管理。运动诱发性哮喘是已知哮喘患者在剧烈运动（通常持续5至10分钟）后出现的短暂气道狭窄的传统术语，肺功能至少下降10%。在哮喘患者中，运动诱发性哮喘将被称为运动诱发性支气管痉挛。运动诱发性支气管痉挛（EIB）在无已知哮喘的个体中是相同的现象。EIB可见于包括儿童在内的健康个体，以及新兵和竞技或精英运动员。阐述了结合病史通过客观运动激发试验方法进行的诊断。管理的特点是针对潜在哮喘、运动诱发性支气管痉挛和吸入性过敏采取药物治疗和非药物治疗措施。如果哮喘得到妥善管理，儿童可以成功参与所有运动。
