Tikhonova S N, Vasil'chenko V N, Vendt V P, Leont'ev V S, Vasil'chenko N S
Ukr Biokhim Zh. 1976 Apr-Jun;48(3):332-6.
Proliferaiton of thymus-dependent lymphocytes and immunological reaction of the line CBA mice immunized with sheep erythrocytes was studied as affected by thymosterol A. The data obtained confirmed the authors' assumptions on a stimulation effect of thymosterol A on division of thymocytes. Introduction of the mentioned preparation against a background of the antigenic aciton of sheep erythrocytes causes an increase in the amount of cells synthesizing hemolysins more than by 60% as compared to the control. The preparation effect depends on the dose. The data are presented, which makes it possible to assume that the mentioned effects may be due to the action of thymosterol A on the content and activity of the intracellular cyclic AMP.
研究了胸腺甾醇A对依赖胸腺淋巴细胞增殖以及用绵羊红细胞免疫的CBA品系小鼠免疫反应的影响。所获数据证实了作者关于胸腺甾醇A对胸腺细胞分裂具有刺激作用的假设。在绵羊红细胞抗原作用的背景下引入上述制剂，与对照组相比，合成溶血素的细胞数量增加超过60%。制剂效果取决于剂量。所呈现的数据使得可以假设上述效应可能归因于胸腺甾醇A对细胞内环磷酸腺苷含量和活性的作用。
