Thuyne Wim Van, Delbeke Frans T
Doping Control Laboratory, Department of Clinical Chemistry, Microbiology, and Immunology, Ghent University--UGent, Ghent, Belgium.
Clin J Sport Med. 2008 Mar;18(2):143-7. doi: 10.1097/JSM.0b013e318163f220.
To assess and compare the prevalence of declared medication, such as corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs), beta2-agonists, narcotic analgesics, anaesthetics, and antidepressant drugs, in time and between different sports among athletes tested for doping control in a 4-year period.
Survey study.
Belgium.
This paper reviews the data obtained from 18,645 doping control forms gathered between 2002 and 2005 from national doping organisations in Belgium and The Netherlands, the International Cycling Union (UCI), and the Belgian Cycling Federation.
All athletes were asked by doping control officers to declare the medication taken in the last 3 days before competition after which the doping control forms were double blinded and handed over to the laboratory.
Classification of declared medication according to the active ingredient.
The overall declared use of medication belonging to one of the monitored categories increased from 19.8% in 2002 to 24.67% in 2005. Differences in use of medication were observed between sports with a higher prevalence of use of NSAIDs in ball sports compared to other sports and a higher use of beta-agonists and corticosteroids in cycling with percentages of declared corticosteroid use in samples from the UCI exceeding 36% in 2005.
These results indicate that the current granting of therapeutic use exemption for corticosteroids and beta-agonists needs to be revised and that threshold levels for beta-agonists should be implemented.
评估并比较在4年期间接受兴奋剂检测的运动员中，已申报使用的药物（如皮质类固醇、非甾体抗炎药、β2-激动剂、麻醉性镇痛药、麻醉剂和抗抑郁药）的使用情况及不同运动项目之间的差异。
调查研究。
比利时。
本文回顾了2002年至2005年期间从比利时和荷兰的国家反兴奋剂组织、国际自行车联盟（UCI）以及比利时自行车联合会收集的18645份兴奋剂检测表格中的数据。
兴奋剂检测官员要求所有运动员申报比赛前最后3天服用的药物，之后对兴奋剂检测表格进行双盲处理并送交实验室。
根据活性成分对已申报药物进行分类。
属于监测类别的已申报药物总体使用率从2002年的19.8%上升至2005年的24.67%。不同运动项目之间存在用药差异，球类运动中使用非甾体抗炎药的比例高于其他运动项目，自行车运动中使用β-激动剂和皮质类固醇的比例较高，2005年国际自行车联盟样本中已申报皮质类固醇的使用比例超过36%。
这些结果表明，目前对皮质类固醇和β-激动剂的治疗性使用豁免规定需要修订，并且应实施β-激动剂的阈值水平。
