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挪威反兴奋剂机构在五年时间里对运动员进行药物检测的情况。

Use of pharmaceuticals amongst athletes tested by Anti-Doping Norway in a five-year period.

作者信息

Gjelstad Astrid, Herlofsen Tine Marie, Bjerke Anne-Linn, Lauritzen Fredrik, Björnsdottir Ingunn

机构信息

Science and Medicine, Anti-Doping Norway, Oslo, Norway.

Department of Pharmaceutical Chemistry, School of Pharmacy, University of Oslo, Oslo, Norway.

出版信息

Front Sports Act Living. 2023 Oct 4;5:1260806. doi: 10.3389/fspor.2023.1260806. eCollection 2023.

Abstract

INTRODUCTION

The aim of the study was to map the use of pharmaceuticals by Norwegian athletes registered on doping control forms (DCFs) in a five-year period to examine general and some class specific use of pharmaceuticals across sports and athlete levels.

METHOD

Anonymous data from DCFs collected in 2015-2019 were manually entered into a database using the Anatomical Therapeutic Chemical (ATC) system for classification of the pharmaceuticals. Variables entered were year of control, gender, age group, athlete level, sport, test type, nationality, and pharmaceuticals (and dietary supplements) used.

RESULTS

Pain killers in the ATC groups M01 A (Nonsteroidal anti-inflammatory drugs - NSAIDs) and N02 B (other analgesics), and anti-asthmatics in ATC groups R03 A and R03 B were the most frequently used pharmaceuticals. National level athletes reported more use of pharmaceuticals (1.4 ± 1.7 pharmaceuticals per form) than recreational level athletes (0.9 ± 1.2). The highest proportion of DCFs containing information about at least one pharmaceutical were found in speed skating (79.1%), alpine skiing (74.0%), rowing (72.4%) and cross-country skiing (71.7%). Painkillers were most frequently used in muscular endurance sports (30.4% and 21.2 % for M01A and N02 B, respectively) and ball and team sports (17.9% and 17.0%). Use of hypnotics was reported from ice-hockey players and alpine skiers in around 8% of the cases.

COCLUSION

Use of anti-asthmatics was most often reported amongst athletes specially exposed to cold, chemicals and heavy endurance training. Athletes in specialized sports requiring high levels of strength and/or endurance reported a higher use of pharmaceuticals out-of-competition compared to in-competition, while there was no such difference in complex sports, such as team, gymnastic, aiming and combat sports.

摘要

引言

本研究的目的是绘制挪威运动员在五年内填写的兴奋剂检查表格(DCF)中药物使用情况,以研究不同运动项目和运动员水平中药物的总体使用情况以及某些特定类别药物的使用情况。

方法

将2015年至2019年收集的DCF中的匿名数据手动录入数据库,使用解剖学治疗化学(ATC)系统对药物进行分类。录入的变量包括检查年份、性别、年龄组、运动员水平、运动项目、检测类型、国籍以及使用的药物(和膳食补充剂)。

结果

ATC组M01 A(非甾体抗炎药 - NSAIDs)和N02 B(其他镇痛药)中的止痛药,以及ATC组R03 A和R03 B中的抗哮喘药是最常用的药物。国家级运动员报告使用的药物(每份表格1.4±1.7种药物)比业余水平运动员(0.9±1.2种)更多。在速度滑冰(79.1%)、高山滑雪(74.0%)、赛艇(72.4%)和越野滑雪(71.7%)中,含有至少一种药物信息的DCF比例最高。止痛药在肌肉耐力运动(M01A和N02 B分别为30.4%和21.2%)以及球类和团队运动(17.9%和17.0%)中使用最为频繁。约8%的冰球运动员和高山滑雪运动员报告使用过催眠药。

结论

抗哮喘药的使用在特别暴露于寒冷、化学物质和高强度耐力训练的运动员中最为常见报道。与比赛期间相比,需要高水平力量和/或耐力的专项运动项目中的运动员在非比赛期间报告使用药物的情况更多,而在团队、体操、射击和格斗等综合运动项目中则没有这种差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6493/10582642/fdee24ec232a/fspor-05-1260806-g001.jpg

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