Oncology, Royal Free and University College Medical School, London, UK.
HPB (Oxford). 2007;9(2):104-11. doi: 10.1080/13651820701216216.
Biliary tract cancers are uncommon malignancies arising from biliary epithelium intrahepatically (peripheral cholangiocarcinoma), in the extrahepatic bile duct, the gall bladder and the ampulla of Vater. Treatment has been challenging because of late presentation, complex surgery, complex biliary obstruction with jaundice and a paucity of high quality data on which to establish standard care. With improvements in imaging, biliary stenting, surgical management and the establishment of a national investigational programme we hope to define the modern management of biliary tract cancers and enable a platform for further research.
胆道癌是一种罕见的恶性肿瘤,起源于肝内胆管上皮(周围性胆管癌)、肝外胆管、胆囊和 Vater 壶腹。由于晚期表现、复杂的手术、伴有黄疸的复杂胆道阻塞以及缺乏高质量的数据来确定标准治疗,治疗一直具有挑战性。随着影像学、胆道支架、手术管理的改进以及国家研究计划的建立,我们希望能够确定胆道癌的现代治疗方法,并为进一步的研究提供平台。