• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

胆道癌的治疗新进展。

New advances in the management of biliary tract cancer.

机构信息

Oncology, Royal Free and University College Medical School, London, UK.

出版信息

HPB (Oxford). 2007;9(2):104-11. doi: 10.1080/13651820701216216.

DOI:10.1080/13651820701216216
PMID:18333124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2020788/
Abstract

Biliary tract cancers are uncommon malignancies arising from biliary epithelium intrahepatically (peripheral cholangiocarcinoma), in the extrahepatic bile duct, the gall bladder and the ampulla of Vater. Treatment has been challenging because of late presentation, complex surgery, complex biliary obstruction with jaundice and a paucity of high quality data on which to establish standard care. With improvements in imaging, biliary stenting, surgical management and the establishment of a national investigational programme we hope to define the modern management of biliary tract cancers and enable a platform for further research.

摘要

胆道癌是一种罕见的恶性肿瘤,起源于肝内胆管上皮(周围性胆管癌)、肝外胆管、胆囊和 Vater 壶腹。由于晚期表现、复杂的手术、伴有黄疸的复杂胆道阻塞以及缺乏高质量的数据来确定标准治疗,治疗一直具有挑战性。随着影像学、胆道支架、手术管理的改进以及国家研究计划的建立,我们希望能够确定胆道癌的现代治疗方法,并为进一步的研究提供平台。

相似文献

1
New advances in the management of biliary tract cancer.胆道癌的治疗新进展。
HPB (Oxford). 2007;9(2):104-11. doi: 10.1080/13651820701216216.
2
[Surgical treatment of cancer of the biliary tract and gall bladder].[胆道和胆囊癌的外科治疗]
Gan To Kagaku Ryoho. 1991 Jul;18(8):1264-8.
3
Imaging of malignancies of the biliary tract- an update.胆道恶性肿瘤的影像学——最新进展
Cancer Imaging. 2014 Apr 22;14(1):14. doi: 10.1186/1470-7330-14-14.
4
Carcinoembryonic antigen (CEA) in benign and malignant epithelium of the gall bladder, extrahepatic bile ducts, and ampulla of Vater.胆囊、肝外胆管和十二指肠乳头的良性及恶性上皮组织中的癌胚抗原(CEA)
J Pathol. 1993 May;170(1):73-6. doi: 10.1002/path.1711700112.
5
Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers.c-erbB-2、表皮生长因子受体和c-met在胆管癌中的扩增及过表达。
J Pathol. 2005 Jul;206(3):356-65. doi: 10.1002/path.1779.
6
Trends in biliary tract cancer.胆道癌的趋势
Rev Epidemiol Sante Publique. 1993;41(2):113-22.
7
Biliary tract malignancies: a population-based study on incidence, prognosis and management of patients.胆道恶性肿瘤:一项基于人群的患者发病率、预后及管理的研究
Scand J Gastroenterol. 2016 Dec;51(12):1520-1525. doi: 10.1080/00365521.2016.1218538. Epub 2016 Aug 24.
8
Descriptive study of gallbladder, extrahepatic bile duct, and ampullary cancers in the United States, 1997-2002.1997 - 2002年美国胆囊癌、肝外胆管癌和壶腹癌的描述性研究。
Cancer Causes Control. 2007 May;18(4):415-22. doi: 10.1007/s10552-006-0109-4. Epub 2007 Jan 30.
9
[A retrospective analysis of ultrasonic diagnosis for 360 cases of extrahepatic obstructive jaundice].360例肝外阻塞性黄疸的超声诊断回顾性分析
Zhonghua Yi Xue Za Zhi. 2014 Aug 26;94(32):2522-4.
10
Polymorphisms of genes in the lipid metabolism pathway and risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, China.脂质代谢途径基因多态性与胆道癌及结石风险:基于中国上海人群的病例对照研究
Cancer Epidemiol Biomarkers Prev. 2008 Mar;17(3):525-34. doi: 10.1158/1055-9965.EPI-07-2704. Epub 2008 Feb 22.

引用本文的文献

1
Austrian tricentric real-life analysis of molecular profiles of metastatic biliary tract cancer patients.奥地利对转移性胆管癌患者分子特征的三中心真实世界分析。
Front Oncol. 2023 May 10;13:1143825. doi: 10.3389/fonc.2023.1143825. eCollection 2023.
2
The Preoperative Assessment of Hepatic Tumours: Evaluation of UK Regional Multidisciplinary Team Performance.肝脏肿瘤的术前评估:英国区域多学科团队表现评估
HPB Surg. 2013;2013:861681. doi: 10.1155/2013/861681. Epub 2013 Aug 22.
3
Adenoma-carcinoma sequence in intrahepatic cholangiocarcinoma.肝内胆管癌的腺瘤-癌序列
Int J Surg Case Rep. 2012;3(4):131-3. doi: 10.1016/j.ijscr.2012.01.002. Epub 2012 Jan 18.
4
Prospective study of MMP7 serum levels in the diagnosis of cholangiocarcinoma.MMP7 血清水平在胆管癌诊断中的前瞻性研究。
World J Gastroenterol. 2010 Oct 7;16(37):4697-703. doi: 10.3748/wjg.v16.i37.4697.

本文引用的文献

1
Gemcitabine alone or in combination with cisplatin in patients with advanced or metastatic cholangiocarcinomas or other biliary tract tumours: a multicentre randomised phase II study - The UK ABC-01 Study.吉西他滨单药或联合顺铂用于晚期或转移性胆管癌或其他胆道肿瘤患者:一项多中心随机II期研究——英国ABC-01研究
Br J Cancer. 2009 Aug 18;101(4):621-7. doi: 10.1038/sj.bjc.6605211.
2
Improved operative and survival outcomes of surgical treatment for hilar cholangiocarcinoma.肝门部胆管癌手术治疗的手术效果及生存结局改善
Br J Surg. 2006 Dec;93(12):1488-94. doi: 10.1002/bjs.5482.
3
Phase III study of 5FU, etoposide and leucovorin (FELV) compared to epirubicin, cisplatin and 5FU (ECF) in previously untreated patients with advanced biliary cancer.在先前未经治疗的晚期胆管癌患者中,5-氟尿嘧啶、依托泊苷和亚叶酸钙(FELV)与表柔比星、顺铂和5-氟尿嘧啶(ECF)的III期研究。
Br J Cancer. 2005 May 9;92(9):1650-4. doi: 10.1038/sj.bjc.6602576.
4
Photodynamic therapy for pancreatic and biliary tract carcinoma.胰腺和胆道癌的光动力疗法
Int J Gastrointest Cancer. 2005;35(1):1-13. doi: 10.1385/IJGC:35:1:001.
5
A randomised phase II trial of weekly high-dose 5-fluorouracil with and without folinic acid and cisplatin in patients with advanced biliary tract carcinoma: results of the 40955 EORTC trial.一项针对晚期胆管癌患者的随机II期试验:每周高剂量5-氟尿嘧啶联合或不联合亚叶酸钙和顺铂的疗效——欧洲癌症研究与治疗组织(EORTC)40955试验结果
Eur J Cancer. 2005 Feb;41(3):398-403. doi: 10.1016/j.ejca.2004.10.026.
6
Enhancement of focal liver lesions at gadoxetic acid-enhanced MR imaging: correlation with histopathologic findings and spiral CT--initial observations.钆塞酸增强磁共振成像中肝脏局灶性病变的强化:与组织病理学结果及螺旋CT的相关性——初步观察
Radiology. 2005 Feb;234(2):468-78. doi: 10.1148/radiol.2342040278. Epub 2004 Dec 10.
7
Transplantation for hilar cholangiocarcinoma.肝门部胆管癌的移植治疗。
Liver Transpl. 2004 Oct;10(10 Suppl 2):S65-8. doi: 10.1002/lt.20266.
8
Major hepatic resection for hilar cholangiocarcinoma: analysis of 46 patients.肝门部胆管癌的扩大肝切除术:46例患者分析
Arch Surg. 2004 May;139(5):514-23; discussion 523-5. doi: 10.1001/archsurg.139.5.514.
9
Outcomes after resection of cholangiocellular carcinoma.胆管细胞癌切除术后的结果。
Am J Surg. 2004 May;187(5):612-7. doi: 10.1016/j.amjsurg.2004.01.007.
10
Mitomycin C in combination with capecitabine or biweekly high-dose gemcitabine in patients with advanced biliary tract cancer: a randomised phase II trial.丝裂霉素C联合卡培他滨或每两周一次大剂量吉西他滨治疗晚期胆管癌患者:一项随机II期试验
Ann Oncol. 2004 Mar;15(3):478-83. doi: 10.1093/annonc/mdh096.