抗凝治疗的当前挑战。

Current challenges of anticoagulant treatment.

作者信息

Ginghină Carmen, Giuşcă S, Serban Marinela, Popescu B A, Jurcuţ Ruxandra, Uscăţescu Valentina

机构信息

"Prof. Dr. C.C. Iliescu" Institute of Cardiovascular Disease, Bucharest, Romania.

出版信息

Rom J Intern Med. 2007;45(3):221-7.

PMID:18333353

Abstract

Anticoagulant therapy plays an important role in current medical practice. The main types of anticoagulant agents are: heparins, hirudins and vitamin K antagonists. None of the drugs used as anticoagulants meet the criteria of an ideal anticoagulant because they have side effects and they interact with other compounds. The main side effect of anticoagulant therapy is bleeding. The choice of a certain anticoagulant is made by the doctor based on the clinical context and also on the desired effect.

摘要

抗凝治疗在当前医学实践中发挥着重要作用。抗凝剂的主要类型有：肝素、水蛭素和维生素K拮抗剂。用作抗凝剂的药物均不符合理想抗凝剂的标准，因为它们有副作用且会与其他化合物相互作用。抗凝治疗的主要副作用是出血。医生会根据临床情况以及预期效果来选择某种抗凝剂。