银杏对钉螺的杀螺活性。
Molluscicidal activity against Oncomelania hupensis of Ginkgo biloba.
作者信息
Yang Xiao-Ming, Chen Sheng-Xia, Xia Lei, Chen Jun
机构信息
School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, PR China.
出版信息
Fitoterapia. 2008 Jun;79(4):250-4. doi: 10.1016/j.fitote.2007.11.030. Epub 2008 Feb 9.
In search for molluscicidal active components, petroleum ether, ethyl acetate, ethanol, and water extracts from Ginkgo sarcotesta were evaluated against the snail Oncomelania hupensis. The bioassay-oriented showed that the activity concentrates in the petroleum ether extract (LD(50) 7.81 ppm). Ginkgolic acids, isolated from the petroleum ether extract, exhibited strong molluscicidal activity (LD(50) 1.49 ppm), gingkgolic acid C15:1 having the strongest molluscicidal activity.
为寻找杀螺活性成分，对银杏外种皮的石油醚、乙酸乙酯、乙醇和水提取物进行了针对钉螺的活性评估。以生物测定为导向的研究表明，活性集中在石油醚提取物中（半数致死剂量为7.81 ppm）。从石油醚提取物中分离出的银杏酸表现出很强的杀螺活性（半数致死剂量为1.49 ppm），其中银杏酸C15:1的杀螺活性最强。
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