Evertson Dale W, Holcomb Mark R, Eames Matthew C, Bray Mark-Anthony, Sidorov Veniamin Y, Xu Junkai, Wingard Holley, Dobrovolny Hana M, Woods Marcella C, Gauthier Daniel J, Wikswo John P
Department of Mechanical Engineering, Vanderbilt University, Nashville, TN 37235, USA.
IEEE Trans Biomed Eng. 2008 Mar;55(3):1241-3. doi: 10.1109/TBME.2007.912417.
A panoramic cardiac imaging system consisting of three high-speed CCD cameras has been developed to image the surface electrophysiology of a rabbit heart via fluorescence imaging using a voltage-sensitive fluorescent dye. A robust, unique mechanical system was designed to accommodate the three cameras and to adapt to the requirements of future experiments. A unified computer interface was created for this application - a single workstation controls all three CCD cameras, illumination, stimulation, and a stepping motor that rotates the heart. The geometric reconstruction algorithms were adapted from a previous cardiac imaging system. We demonstrate the system by imaging a polymorphic cardiac tachycardia.
一种由三个高速电荷耦合器件（CCD）相机组成的全景心脏成像系统已被开发出来，用于通过使用电压敏感染料的荧光成像来对兔心脏的表面电生理学进行成像。设计了一个坚固、独特的机械系统来容纳这三个相机，并适应未来实验的要求。针对此应用创建了一个统一的计算机接口——一个单一的工作站控制所有三个CCD相机、照明、刺激以及一个使心脏旋转的步进电机。几何重建算法改编自先前的心脏成像系统。我们通过对多形性室性心动过速进行成像来展示该系统。
