Hirano Ko, Ueguchi-Tanaka Miyako, Matsuoka Makoto
Bioscience and Biotechnology Center, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
Trends Plant Sci. 2008 Apr;13(4):192-9. doi: 10.1016/j.tplants.2008.02.005. Epub 2008 Mar 11.
Gibberellin (GA) perception is mediated by GID1 (GA-INSENSITIVE DWARF1), a receptor that shows similarity to hormone-sensitive lipases. A key event in GA signaling is the degradation of DELLA proteins, which are negative regulators of GA response that interact with GID1 in a GA-dependent manner. This GID1-DELLA GA-perception system is conserved among vascular plants but is not found in the moss Physcomitrella patens. The identification of factors in GA signaling downstream of DELLA and the development of a new concept of DELLA function beyond its role as a repressor of GA signaling are important advances. DELLA proteins appear to have at least two other distinct roles: maintaining GA homeostasis and regulating cross-talk between GA and other plant hormones.
赤霉素（GA）的感知由GID1（GA不敏感矮化1）介导，GID1是一种与激素敏感脂肪酶具有相似性的受体。GA信号传导中的一个关键事件是DELLA蛋白的降解，DELLA蛋白是GA反应的负调节因子，以GA依赖的方式与GID1相互作用。这种GID1-DELLA GA感知系统在维管植物中是保守的，但在苔藓小立碗藓中未发现。鉴定DELLA下游GA信号传导中的因子以及发展超越其作为GA信号传导阻遏物作用的DELLA功能新概念是重要进展。DELLA蛋白似乎至少还有另外两个不同的作用：维持GA稳态以及调节GA与其他植物激素之间的相互作用。
