Liang Guang-Yi, He Zhu-Ying, Wu Kong-Yun, Jin Feng-Yun, Li Xing, Feng Hua
Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550002, China.
Zhongguo Zhong Yao Za Zhi. 2007 Dec;32(24):2600-3.
To investigate the factors influencing on the ephedrine contents in different compositions of Maxingshigan decoction.
Adopt mixed uniform design to dismantle recipes, employ the stepping regression analysis to deal with experimental statistics, use the partial correlational analysis to analyze the correlation coefficients and the results were validated.
The regressive equation was of significance, that is Y = 4.36719347 + 7.752707437X1 + 1.2557197041X3 (r = 0.85564, P = 0.0189). The main influencing factors on ephedrine content in Maxingshigan decoction were gypsum and amygdalin. The influent factor of amygdalin on ephedrine content had great significance, and gypsum had significance.
The collective effects of amygdalin and gypsum affect the content of ephedrine in Maxing Shigan decoction which the content-effect relationship was in direct correlation.
探讨影响麻杏石甘汤不同配伍中麻黄碱含量的因素。
采用混合均匀设计进行拆方，运用逐步回归分析处理实验数据，采用偏相关分析方法分析相关系数并进行结果验证。
回归方程具有显著性，即Y = 4.36719347 + 7.752707437X1 + 1.2557197041X3（r = 0.85564，P = 0.0189）。影响麻杏石甘汤中麻黄碱含量的主要因素是石膏和苦杏仁苷。苦杏仁苷对麻黄碱含量的影响因素具有高度显著性，石膏具有显著性。
苦杏仁苷与石膏的共同作用影响麻杏石甘汤中麻黄碱的含量，其含量-效应关系呈正相关。
