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[高效液相色谱法测定麻杏石甘汤传统汤剂与颗粒剂中苦杏仁苷的含量]

[Determination of contents of amygdalin in traditional and granular decoctions of Maxingshigan decoction by HPLC].

作者信息

Wu Kong-yun, Liang Guang-yi, He Zhu-ying, Jin Feng-yun, Li Xing, Feng Hua

机构信息

The Key Laboratory of Chemistry for Natural Products of Guizhou Province, Chinese Academy of Sciences, Guiyang 550002, China.

出版信息

Zhong Yao Cai. 2007 Sep;30(9):1128-30.

PMID:18236758
Abstract

OBJECTIVE

To determine the contents of amygdalin in traditional and granular decoctions of Maxingshigan decoction.

METHODS

The determination was carried out by HPLC with an ODS column and a mobile phase of water-methanol (23:77) at 215 nm.

RESULTS

The content of amygdalin in traditional decoction of Maxingshigan Decoction was 17.74 mg/g and 24.80 mg/g in granular one.

CONCLUSION

The content of glycyrrhizic acid in traditional decoction of Maxingshigan decoction is obviously higher than that in granular one.

摘要

目的

测定麻杏石甘汤传统汤剂与颗粒剂中苦杏仁苷的含量。

方法

采用高效液相色谱法,以ODS柱为固定相,水-甲醇(23:77)为流动相,检测波长为215nm进行测定。

结果

麻杏石甘汤传统汤剂中苦杏仁苷的含量为17.74mg/g,颗粒剂中为24.80mg/g。

结论

麻杏石甘汤传统汤剂中甘草酸的含量明显高于颗粒剂。

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