[Clinical aspects of primary malignant melanoma of the vagina].

This is a German case report of 12 patients with malignant melanoma of the vagina. Their median age is 58.3 years. Four out of 12 patients have been treated by radical surgery alone. In 8 patients surgery was restricted to a wide excision. In four cases additional brachytherapy was performed. The prognosis of malignant melanoma of the vagina is extremely poor. Three patients survived for two years following primary therapy. All patients died within 6.5 years after diagnosis and initial treatment. In our experience and according to literature radical surgery seemingly achieves the best results within the limited prognosis of this disease.