Kaku S, Pinto F, Agualusa A, Sampayo F
Serviço de Cardiologia Pediátrica dos Hospitals Civis de Lisboa, Hospital de Santa Marta.
Rev Port Cardiol. 1991 Jun;10(6):517-22.
Assessment of the results of percutaneous transluminal balloon pulmonary valvuloplasty (BPV) in children.
Retrospective analysis of the methodology and results between October 1985 and October 1990. SITE OF THE STUDY: Pediatric Cardiology Service, Santa Marta Hospital, Lisbon.
43 consecutive children with pulmonary valve stenosis. 4 children with Noonan's Syndrome were excluded from the study and the results of 45 valvuloplasties in 39 patients are analysed.
Full diagnostic catheterization and right ventricular cineangiography were performed. One or two balloon dilatation catheters were inserted percutaneously in one or both femoral veins and positioned across the pulmonary valve under fluoroscopic control. The balloons were then inflated to their maximum pressure with diluted contrast medium. In 18 children follow up cardiac catheterization was performed 3 to 12 months after valvuloplasty (mean 6.7 /+- 2.7).
A satisfactory dilatation was achieved in 35 patients (89%) with a substantial decrease in right ventricular systolic pressure (RVP) and in transvalvar peak systolic gradient (GR) (p less than 0.0001). A further significant spontaneous reduction in RVP and GR was recorded on follow up catheterization (p less than 0.01). A repeat BVP was performed in 6 children and was successful in 5. In cases a satisfactory relief of the stenosis was not achieved and 3 of them were submitted to surgery. There were no deaths. One child had cardiac arrest leading to successful surgical valvotomy and with no sequelae. Another child had cerebral embolism with hemiparesis. Ligation of a femoral vein was required in one case for haemorrhage. Mild pulmonary insufficiency resulted in 15 children.
Our experience confirms that BPV is the method of choice for the treatment of children with pulmonary valve stenosis either isolated or associated to small ventricular septal defect. It proved to be a safe and effective technique for reduction of GR. Mortality, morbidity, costs of the treatment and hospitalisation time are lower for BPV than for surgery with comparable short term results.
评估儿童经皮腔内球囊肺动脉瓣成形术(BPV)的结果。
对1985年10月至1990年10月间的方法和结果进行回顾性分析。
里斯本圣玛尔塔医院儿科心脏病科。
43例连续性肺动脉瓣狭窄患儿。4例努南综合征患儿被排除在研究之外,分析了39例患者45次瓣膜成形术的结果。
进行全面的诊断性心导管检查和右心室血管造影。经皮将一或两根球囊扩张导管插入一侧或双侧股静脉,并在荧光透视控制下将其置于肺动脉瓣处。然后用稀释的造影剂将球囊充至最大压力。18例患儿在瓣膜成形术后3至12个月(平均6.7±2.7)进行了随访心导管检查。
35例患者(89%)实现了满意的扩张,右心室收缩压(RVP)和跨瓣收缩期峰值梯度(GR)显著降低(p<0.0001)。随访心导管检查记录到RVP和GR进一步显著自发性降低(p<0.01)。6例患儿进行了重复BPV,5例成功。在未实现狭窄满意缓解的病例中,其中3例接受了手术。无死亡病例。1例患儿发生心脏骤停,成功进行了手术瓣膜切开术,无后遗症。另1例患儿发生脑栓塞并伴有偏瘫。1例因出血需要结扎股静脉。15例患儿出现轻度肺动脉瓣关闭不全。
我们的经验证实,BPV是治疗孤立性或合并小型室间隔缺损的肺动脉瓣狭窄患儿的首选方法。它被证明是一种降低GR的安全有效的技术。与手术相比,BPV的死亡率、发病率、治疗成本和住院时间更低,短期结果相当。