Bogucki A, Janczewska E, Koszewska I, Chmielowski M, Szymańska R
Department of Neurology, Medical Academy, Lódź, Poland.
Eur Arch Psychiatry Clin Neurosci. 1991;241(2):91-7. doi: 10.1007/BF02191148.
Sixteen patients with a clinical diagnosis of subcortical arteriosclerotic encephalopathy (Binswanger's disease) were studied. Mild or moderate dementia was found in 14 cases, with characteristic disturbances of concentration, and psychic retardation with apathy. Neuropsychological studies revealed that signs of diffuse lesions in the frontal lobes dominated. Impairment of memory was significant in all cases. Although intellectual impairment in subcortical arteriosclerotic encephalopathy resembled subcortical dementia, some significant differences were found.
对16例临床诊断为皮质下动脉硬化性脑病（宾斯旺格病）的患者进行了研究。14例患者存在轻度或中度痴呆，伴有注意力集中的特征性障碍、精神迟滞及淡漠。神经心理学研究显示，额叶弥漫性病变的体征占主导。所有病例均有明显的记忆损害。尽管皮质下动脉硬化性脑病的智力损害类似于皮质下痴呆，但仍发现了一些显著差异。
