病生菜：意外服用乌头碱导致恶性室性心律失常。
Salade malade: malignant ventricular arrhythmias due to an accidental intoxication with Aconitum napellus.
机构信息
Department of Cardiology, Máxima Medical Centre, Veldhoven, the Netherlands.
出版信息
Neth Heart J. 2008;16(3):96-9. doi: 10.1007/BF03086125.
Abstract
Intoxication with Aconitum napellus is rare in our regions. Aconite alkaloids can cause ventricular arrhythmia by a prolonged activation of sodium channels. Because the margin of safety is low between the analgesic and toxic dose, intoxication is not rare when Aconite is used in herbal medicine. We present a case in which a 39-year-old male was accidentally intoxicated with Aconite. Even though no antidote or adequate therapy is available he was successfully resuscitated. (Neth Heart J 2008;16:96-9.).
摘要
我们所在地区阿寇酮中毒较为罕见。阿寇碱能通过延长钠离子通道的激活时间引发室性心律失常。由于阿寇酮的镇痛剂量和中毒剂量之间的安全范围较窄，因此在草药医学中阿寇酮中毒并不罕见。我们报告了 1 例 39 岁男性意外阿寇酮中毒的病例。尽管没有解毒剂或适当的治疗方法，但患者成功复苏。（Neth Heart J 2008;16:96-9.）。
相似文献
1
Salade malade: malignant ventricular arrhythmias due to an accidental intoxication with Aconitum napellus.病生菜：意外服用乌头碱导致恶性室性心律失常。
Neth Heart J. 2008;16(3):96-9. doi: 10.1007/BF03086125.
2
[Intoxication with Monkshood (Aconitum napellus)].[乌头（附子）中毒]
Ned Tijdschr Geneeskd. 2009;153:A387.
3
Aconite poisoning.乌头中毒
Clin Toxicol (Phila). 2009 Apr;47(4):279-85. doi: 10.1080/15563650902904407.
4
The management of ventricular dysrhythmia in aconite poisoning.乌头中毒时室性心律失常的处理
Clin Toxicol (Phila). 2017 Jun;55(5):313-321. doi: 10.1080/15563650.2017.1291944. Epub 2017 Feb 20.
5
[High-dose magnesium sulfate in the treatment of aconite poisoning].[大剂量硫酸镁治疗乌头中毒]
Anaesthesist. 2015 May;64(5):381-4. doi: 10.1007/s00101-015-0013-y. Epub 2015 Mar 27.
6
Recurrent ventricular arrhythmia due to aconite intoxication successfully treated with landiolol: A case report.用兰地洛尔成功治疗乌头碱中毒所致复发性室性心律失常：一例报告
World J Clin Cases. 2023 Aug 6;11(22):5303-5308. doi: 10.12998/wjcc.v11.i22.5303.
7
Cardiotoxicity after accidental herb-induced aconite poisoning.意外草药致乌头中毒后的心脏毒性。
Lancet. 1992 Nov 21;340(8830):1254-6. doi: 10.1016/0140-6736(92)92951-b.
8
[Long QRS tachycardia secondary to Aconitum napellus alkaloid ingestion].[因摄入乌头生物碱继发的长QRS波心动过速]
Ital Heart J Suppl. 2002 Aug;3(8):874-7.
9
An accidental case of aconite poisoning due to Kampo herbal medicine ingestion.一例因服用汉方药导致乌头中毒的意外病例。
Leg Med (Tokyo). 2009 May;11(3):132-5. doi: 10.1016/j.legalmed.2008.11.001. Epub 2009 Jan 1.
10
[Aconite, in 4.50 from Paddington: Continuous Activation of Voltage-Gated Sodium Channel].[来自帕丁顿的乌头碱，浓度为4.50：电压门控钠通道的持续激活]
Brain Nerve. 2023 Dec;75(12):1335-1338. doi: 10.11477/mf.1416202534.
引用本文的文献
1
A Case of High-Dose Intravenous MgSO and Hemoperfusion for Aconite Poisoning with Chronic Kidney Disease.1例大剂量静脉注射硫酸镁及血液灌流治疗乌头碱中毒合并慢性肾脏病的病例
Yonago Acta Med. 2024 Aug 8;67(3):270-279. doi: 10.33160/yam.2024.08.012. eCollection 2024 Aug.
2
An Unexpected Cause of Cardiotoxicity: Kombucha Tea.心脏毒性的一个意外原因：康普茶。
Anatol J Cardiol. 2022 Jun;26(6):492-494. doi: 10.5152/AnatolJCardiol.2022.1463.
3
Poisonous or non-poisonous plants? DNA-based tools and applications for accurate identification.有毒植物还是无毒植物？基于DNA的准确鉴定工具及应用
Int J Legal Med. 2017 Jan;131(1):1-19. doi: 10.1007/s00414-016-1460-y. Epub 2016 Oct 30.
4
Aconite poisoning over 5 years: a case series in Hong Kong and lessons towards herbal safety.乌头碱中毒超过 5 年：香港的一个病例系列及草药安全性的相关经验教训。
Drug Saf. 2012 Jul 1;35(7):575-87. doi: 10.2165/11597470-000000000-00000.
本文引用的文献
1
Clinical features and management of herb-induced aconitine poisoning.草药致乌头碱中毒的临床特征与处理
Ann Emerg Med. 2004 May;43(5):574-9. doi: 10.1016/j.annemergmed.2003.10.046.
2
Malignant ventricular arrhythmias due to Aconitum napellus seeds.乌头种子所致恶性室性心律失常
Circulation. 2000 Dec 5;102(23):2907-8. doi: 10.1161/01.cir.102.23.2907.
3
Successful treatment of aconitine induced life threatening ventricular tachyarrhythmia with amiodarone.胺碘酮成功治疗乌头碱诱发的危及生命的室性快速心律失常
Heart. 2000 Oct;84(4):E8. doi: 10.1136/heart.84.4.e8.
4
Cardiotoxicity after accidental herb-induced aconite poisoning.意外草药致乌头中毒后的心脏毒性。
Lancet. 1992 Nov 21;340(8830):1254-6. doi: 10.1016/0140-6736(92)92951-b.
Zotero 插件