Department of Cardiology, Máxima Medical Centre, Veldhoven, the Netherlands.
Neth Heart J. 2008;16(3):96-9. doi: 10.1007/BF03086125.
Intoxication with Aconitum napellus is rare in our regions. Aconite alkaloids can cause ventricular arrhythmia by a prolonged activation of sodium channels. Because the margin of safety is low between the analgesic and toxic dose, intoxication is not rare when Aconite is used in herbal medicine. We present a case in which a 39-year-old male was accidentally intoxicated with Aconite. Even though no antidote or adequate therapy is available he was successfully resuscitated. (Neth Heart J 2008;16:96-9.).
我们所在地区阿寇酮中毒较为罕见。阿寇碱能通过延长钠离子通道的激活时间引发室性心律失常。由于阿寇酮的镇痛剂量和中毒剂量之间的安全范围较窄,因此在草药医学中阿寇酮中毒并不罕见。我们报告了 1 例 39 岁男性意外阿寇酮中毒的病例。尽管没有解毒剂或适当的治疗方法,但患者成功复苏。(Neth Heart J 2008;16:96-9.)。