Graves William W, Grabowski Thomas J, Mehta Sonya, Gupta Prahlad
Medical College of Wisconsin, Neuro Lab, Milwaukee, WI 53226, USA.
J Cogn Neurosci. 2008 Sep;20(9):1698-710. doi: 10.1162/jocn.2008.20113.
Impairments in phonological processing have been associated with damage to the region of the left posterior superior temporal gyrus (pSTG), but the extent to which this area supports phonological processing, independent of semantic processing, is less clear. We used repetition priming and neural repetition suppression during functional magnetic resonance imaging (fMRI) in an auditory pseudoword repetition task as a semantics-free model of lexical (whole-word) phonological access. Across six repetitions, we observed repetition priming in terms of decreased reaction time and repetition suppression in terms of reduced neural activity. An additional analysis aimed at sublexical phonology did not show significant effects in the areas where repetition suppression was observed. To test if these areas were relevant to real word production, we performed a conjunction analysis with data from a separate fMRI experiment which manipulated word frequency (a putative index of lexical phonological access) in picture naming. The left pSTG demonstrated significant effects independently in both experiments, suggesting that this area participates specifically in accessing lexical phonology.
语音处理障碍与左侧后颞上回（pSTG）区域的损伤有关，但该区域在多大程度上支持语音处理（独立于语义处理）尚不清楚。我们在功能磁共振成像（fMRI）期间，通过听觉假词重复任务中的重复启动和神经重复抑制，作为词汇（整词）语音通达的无语义模型。在六次重复过程中，我们观察到反应时间缩短方面的重复启动以及神经活动减少方面的重复抑制。针对次词汇语音学的额外分析在观察到重复抑制的区域未显示出显著影响。为了测试这些区域是否与真实单词生成相关，我们将来自一个单独的fMRI实验的数据进行联合分析，该实验在图片命名中操纵了单词频率（词汇语音通达的一个假定指标）。左侧pSTG在两个实验中均独立显示出显著影响，表明该区域特别参与词汇语音的通达。
