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乳腺癌复发中的压力与生活质量:应对方式的调节作用还是中介作用?

Stress and quality of life in breast cancer recurrence: moderation or mediation of coping?

作者信息

Yang Hae-Chung, Brothers Brittany M, Andersen Barbara L

机构信息

Department of Psychology, The Ohio State University, 1835 Neil Avenue, Columbus, OH 43210-1222, USA.

出版信息

Ann Behav Med. 2008 Apr;35(2):188-97. doi: 10.1007/s12160-008-9016-0. Epub 2008 Mar 7.

Abstract

BACKGROUND/PURPOSE: Diagnosis with breast cancer recurrence often brings high levels of stress. Successful coping to alleviate stress could improve patients' quality of life (QoL). The intervening role coping plays between stress and QoL may depend on the types of stress encountered and the types of coping strategies used. The present study investigates the longitudinal relationships between stress, coping, and mental health QoL.

METHODS

Breast cancer patients recently diagnosed with recurrence (N = 65) were assessed shortly after the diagnosis and 4 months later. Four moderation and four mediation models were tested using hierarchical multiple regressions and path analyses. In the models, either traumatic stress or symptom-related stress at recurrence diagnosis was a predictor of mental health QoL at follow-up. Both engagement and disengagement coping strategies were tested as moderators or mediators between stress and QoL.

RESULTS

Engagement coping moderated the effect of symptom stress on mental health QoL, whereas disengagement coping mediated the effects of both traumatic stress and symptom stress on mental health QoL.

CONCLUSION

The findings imply that interventions teaching engagement coping strategies would be important for patients experiencing high symptom stress, while discouraging the use of disengagement coping strategies would be important for all patients.

摘要

背景/目的:乳腺癌复发的诊断常常会带来高度的压力。成功应对以减轻压力可以改善患者的生活质量(QoL)。应对在压力和生活质量之间所起的中介作用可能取决于所遇到的压力类型和所使用的应对策略类型。本研究调查了压力、应对和心理健康生活质量之间的纵向关系。

方法

对最近被诊断为复发的乳腺癌患者(N = 65)在诊断后不久及4个月后进行评估。使用分层多元回归和路径分析测试了四个调节模型和四个中介模型。在这些模型中,复发诊断时的创伤性压力或症状相关压力是随访时心理健康生活质量的预测指标。参与性应对策略和脱离性应对策略均作为压力和生活质量之间的调节变量或中介变量进行测试。

结果

参与性应对调节了症状压力对心理健康生活质量的影响,而脱离性应对介导了创伤性压力和症状压力对心理健康生活质量的影响。

结论

研究结果表明,对于经历高症状压力的患者,教授参与性应对策略的干预措施很重要,而对于所有患者而言, discouraging the use of disengagement coping strategies would be important(此处英文表述有误,推测可能是“ discouraging the use of disengagement coping strategies would be important”,意为“不鼓励使用脱离性应对策略很重要”) 。

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