全膝关节置换术后连续股神经阻滞的刺激导管:一项随机、对照、双盲试验。

Stimulating catheters for continuous femoral nerve blockade after total knee arthroplasty: a randomized, controlled, double-blinded trial.

作者信息

Barrington Michael J, Olive David J, McCutcheon Craig A, Scarff Christopher, Said Simone, Kluger Roman, Gillett Nicola, Choong Peter

机构信息

Department of Anaesthesia, St. Vincent's Hospital, PO Box 2900 Fitzroy, Victoria 3065, Melbourne, Australia.

出版信息

Anesth Analg. 2008 Apr;106(4):1316-21, table of contents. doi: 10.1213/ane.0b013e318164efd1.

Abstract

BACKGROUND

Continuous femoral nerve blockade (CFNB) is often used for postoperative analgesia after total knee arthroplasty (TKA). CFNB can be instituted using a variety of techniques. Stimulating catheters (SC) have the advantage of confirming placement of the catheter close to the nerve during advancement.

METHODS

In this randomized, controlled, double-blind trial, we compared a SC with a nonstimulating catheter (NSC) technique for institution of CFNB and its effects on quality of analgesia after TKA performed under general anesthesia in 82 patients. Patients were randomized to have CFNB instituted using either a NSC or a SC technique. Sensory blockade was assessed 10 and 20 min after injection of lidocaine via femoral catheter and on postoperative days 1 (POD 1) and 2 (POD 2). A standardized multimodal analgesic technique, including a single injection sciatic block (preoperative), i.v. morphine (patient-controlled analgesia), celecoxib, and paracetamol, was administered to all patients. Outcome variables included morphine requirements, pain scores, and markers of early recovery.

RESULTS

The proportion of patients with sensory blockade in the femoral nerve distribution was between 90% and 95% at all measurement times with no difference between groups. In the first 24 h, the NSC group required 19.5 (1-67) [median (10th-90th centiles)] mg morphine compared with the SC Group 18 (2-51) mg (P = 0.69). At 24 h, the 95% confidence interval for difference in morphine consumption between groups was -8 to 5 mg. There was no difference between groups in visual analog scale scores at rest on POD 1 and POD 2, during active and passive physiotherapy; and in markers of early recovery after surgery.

CONCLUSIONS

In this study, blind catheter advancement was as reliable as a SC technique for establishing and maintaining CFNB for postoperative analgesia as a part of multimodal analgesia technique after TKA.

摘要

背景

连续股神经阻滞(CFNB)常用于全膝关节置换术(TKA)后的术后镇痛。CFNB可通过多种技术实施。刺激导管(SC)具有在推进过程中确认导管靠近神经位置的优势。

方法

在这项随机、对照、双盲试验中,我们比较了SC技术与非刺激导管(NSC)技术用于实施CFNB及其对82例在全身麻醉下进行TKA术后镇痛质量的影响。患者被随机分为使用NSC技术或SC技术进行CFNB。在通过股导管注射利多卡因后10分钟和20分钟以及术后第1天(POD 1)和第2天(POD 2)评估感觉阻滞情况。对所有患者采用标准化的多模式镇痛技术,包括单次注射坐骨神经阻滞(术前)、静脉注射吗啡(患者自控镇痛)、塞来昔布和对乙酰氨基酚。结果变量包括吗啡需求量、疼痛评分和早期恢复指标。

结果

在所有测量时间点,股神经分布区域有感觉阻滞的患者比例在90%至95%之间,两组之间无差异。在最初24小时内,NSC组需要19.5(1 - 67)[中位数(第10 - 90百分位数)]毫克吗啡,而SC组为18(2 - 51)毫克(P = 0.69)。在24小时时,两组间吗啡消耗量差异的95%置信区间为 - 8至5毫克。在POD 1和POD 2静息时、主动和被动物理治疗期间的视觉模拟量表评分以及术后早期恢复指标方面,两组之间无差异。

结论

在本研究中,作为TKA后多模式镇痛技术的一部分,盲目推进导管在建立和维持CFNB用于术后镇痛方面与SC技术一样可靠。

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