Hirst G C, Lang S A, Dust W N, Cassidy J D, Yip R W
Department of Anesthesia, Royal University Hospital, Saskatoon, Saskatchewan, Canada.
Reg Anesth. 1996 Jul-Aug;21(4):292-7.
This study was conducted to ascertain whether there is any advantage to the continuous-infusion femoral 3-in-1 nerve block over the single-injection femoral nerve block for postoperative analgesia after total knee arthroplasty.
A double-blind, randomized, controlled study was made of 33 patients undergoing total knee arthroplasty, who were randomized into three groups. Group 1 received a single-injection femoral 3-in-1 nerve block with 20 mL 0.5% bupivacaine with 1:200,000 epinephrine. Group 2 had a catheter placed in the femoral nerve sheath, through which a continuous femoral 3-in-1 nerve block was established. Group 3 patients served as controls. All blocks were performed and assessed prior to induction of standardized general anesthesia. All patients received morphine via patient-controlled analgesia. Pain was recorded on a 100-mm visual analog scale at rest and with motion of the knee. Opioid consumption and side effects were recorded; P = .05 was considered statistically significant.
In the recovery room, pain scores with motion were lower in the single-injection and continuous-infusion groups (P < .05). There were no significant differences between any of the groups regarding pain scores or morphine requirements beyond the recovery room. The incidence of nausea was higher in the control group. There were no differences between the groups with respect to overall patient satisfaction.
We were unable to confirm improvements in analgesia provided by continuous-infusion femoral 3-in-1 nerve block for total knee arthroplasty except in the recovery room.
本研究旨在确定全膝关节置换术后持续输注股神经三合一阻滞相较于单次注射股神经阻滞在术后镇痛方面是否具有优势。
对33例行全膝关节置换术的患者进行了一项双盲、随机、对照研究,将患者随机分为三组。第一组接受单次注射含1:200,000肾上腺素的20 mL 0.5%布比卡因的股神经三合一阻滞。第二组在股神经鞘内置入导管,通过该导管建立持续股神经三合一阻滞。第三组患者作为对照组。所有阻滞均在诱导标准化全身麻醉前进行并评估。所有患者均通过患者自控镇痛接受吗啡治疗。在静息和膝关节活动时,采用100 mm视觉模拟量表记录疼痛情况。记录阿片类药物的消耗量和副作用;P = 0.05被认为具有统计学意义。
在恢复室,单次注射组和持续输注组的活动时疼痛评分较低(P < 0.05)。在恢复室之外,各小组之间在疼痛评分或吗啡需求量方面无显著差异。对照组恶心的发生率较高。各小组在患者总体满意度方面无差异。
我们无法证实全膝关节置换术后持续输注股神经三合一阻滞在镇痛方面有改善,除了在恢复室。