Singh Iqbal, Singh Arvind, Mittal Gyanendra
Division of Urology, University College of Medical Sciences (University of Delhi) and GTB Hospital, Delhi, India.
J Endourol. 2008 Mar;22(3):427-34. doi: 10.1089/end.2007.0269.
To prospectively evaluate and study the role, relative safety, and effectiveness of "tubeless" percutaneous nephrolithotomy (PCNL) and whether it is really less morbid vis-à-vis PCNL with a nephrostomy tube; to compare the postoperative pain, analgesia requirement, hospital stay, return to work time, and other parameters in patients undergoing tubeless PCNL and standard PCNL.
Sixty selected patients underwent PCNL. A single urologist (IS) was the surgeon, and a resident administered random chit numbers, and recorded pain scores and results of all the chosen parameters. Patients who fulfilled the entry criteria for a tubeless PCNL protocol were randomized to either the omission of a nephrostomy tube (tubeless PCNL with Double-J stent) or to the placement of a 22F nephrostomy tube. The recorded data were analyzed with respect to several parameters.
The mean age, stone burden, and preoperative hemoglobin, blood urea, and serum creatinine values were not significantly different between the two groups. However, the operative time (P < 0.001), analgesia requirement (P < 0.001), and hospital stay and time to return to normal activity (P < 0.001) were significantly lower in the tubeless PCNL group.
Significantly less pain, lower analgesia requirement, and shorter hospital stay with early return to normal activities were observed in the tubeless PCNL group v the primary nephrostomy tube PCNL group. Tubeless PCNL in selected patients is a secure, effective, and less morbid procedure that does not compromise patient safety and concerns. We recommend that tubeless PCNL be the preferred procedure in selected patients for management of nephrolithiasis.
前瞻性评估和研究“无管”经皮肾镜取石术(PCNL)的作用、相对安全性和有效性,以及与留置肾造瘘管的PCNL相比,其并发症是否真的更少;比较接受无管PCNL和标准PCNL患者的术后疼痛、镇痛需求、住院时间、恢复工作时间及其他参数。
60例入选患者接受PCNL。由一名泌尿外科医生(IS)担任手术医生,住院医师发放随机序号,并记录疼痛评分及所有选定参数的结果。符合无管PCNL方案纳入标准的患者被随机分为不放置肾造瘘管组(带双J管的无管PCNL)或放置22F肾造瘘管组。对记录的数据就多个参数进行分析。
两组患者的平均年龄、结石负荷、术前血红蛋白、血尿素和血清肌酐值无显著差异。然而,无管PCNL组的手术时间(P < 0.001)、镇痛需求(P < 0.001)、住院时间及恢复正常活动时间(P < 0.001)均显著更低。
与留置肾造瘘管的PCNL组相比,无管PCNL组患者疼痛明显减轻、镇痛需求降低、住院时间缩短且能更早恢复正常活动。对于选定患者,无管PCNL是一种安全、有效且并发症少的手术,不影响患者安全和相关问题。我们建议,对于选定的肾结石患者,无管PCNL应作为首选手术方式。