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伪装成眼眶蜂窝织炎的自然杀伤/T细胞淋巴瘤。

Natural killer/T-cell lymphoma masquerading as orbital cellulitis.

作者信息

Charton Justin, Witherspoon S Robert, Itani Kamel, Jones F Ray, Marple Bradly, Morse Brian

机构信息

Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9057, USA.

出版信息

Ophthalmic Plast Reconstr Surg. 2008 Mar-Apr;24(2):143-5. doi: 10.1097/IOP.0b013e3181659867.

DOI:10.1097/IOP.0b013e3181659867
PMID:18356722
Abstract

We describe 3 cases of natural killer/T-cell lymphoma that presented by masquerading as orbital cellulitis. All of the patients were examined for pain, fever, proptosis, and motility restriction. Computed tomography of the orbits and sinuses revealed orbital soft-tissue swelling without focal abscess in all 3 cases. Bacterial and fungal cultures were negative in each case and all of the patients had initial improvement on systemic antibiotics, only to relapse several days later. Diagnosis of natural killer/T-cell lymphoma was then made based on biopsy of the orbit or sinus. Natural killer/T-cell lymphoma should be considered in cases of orbital cellulitis or sinusitis that fail to respond to traditional management. Biopsy of the affected region should be performed expeditiously to diagnose this condition. Repeat biopsy may be needed.

摘要

我们描述了3例伪装成眼眶蜂窝织炎的自然杀伤/T细胞淋巴瘤病例。所有患者均接受了疼痛、发热、眼球突出和眼球运动受限方面的检查。眼眶和鼻窦的计算机断层扫描显示,所有3例患者均有眼眶软组织肿胀,但无局灶性脓肿。每例患者的细菌和真菌培养均为阴性,所有患者最初使用全身抗生素后病情有所改善,但几天后均复发。然后根据眼眶或鼻窦活检确诊为自然杀伤/T细胞淋巴瘤。对于对传统治疗无反应的眼眶蜂窝织炎或鼻窦炎病例,应考虑自然杀伤/T细胞淋巴瘤。应迅速对受影响区域进行活检以诊断此病。可能需要重复活检。

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