Freeman Jennifer B, Garcia Abbe M, Coyne Lisa, Ale Chelsea, Przeworski Amy, Himle Michael, Compton Scott, Leonard Henrietta L
Drs. Freeman, Garcia, Coyne, Ale, Przeworski, Himle, and Leonard are with the Bradley Hasbro Children's Research Center, Providence, RI; and Dr. Compton is with Duke University, Durham, NC..
Drs. Freeman, Garcia, Coyne, Ale, Przeworski, Himle, and Leonard are with the Bradley Hasbro Children's Research Center, Providence, RI; and Dr. Compton is with Duke University, Durham, NC.
J Am Acad Child Adolesc Psychiatry. 2008 May;47(5):593-602. doi: 10.1097/CHI.0b013e31816765f9.
To examine the relative efficacy of family-based cognitive-behavioral therapy (CBT) versus family-based relaxation treatment (RT) for young children ages 5 to 8 years with obsessive-compulsive disorder (OCD).
Forty-two young children with primary OCD were randomized to receive 12 sessions of family-based CBT or family-based RT. Assessments were conducted before and after treatment by independent raters blind to treatment assignment. Primary outcomes included scores on the Children's Yale-Brown Obsessive Compulsive Scale and Clinical Global Impressions-Improvement.
For the intent-to-treat sample, CBT was associated with a moderate treatment effect (d = 0.53), although there was not a significant difference between the groups at conventional levels. For the completer sample, CBT had a large effect (d = 0.85), and there was a significant group difference favoring CBT. In the intent-to-treat sample, 50% of children in the CBT group achieved remission as compared to 20% in the RT group. In the completer sample, 69% of children in the CBT group achieved a clinical remission compared to 20% in the RT group.
Results indicate that children with early-onset OCD benefit from a treatment approach tailored to their developmental needs and family context. CBT was effective in reducing OCD symptoms and in helping a large number of children achieve a clinical remission.
研究基于家庭的认知行为疗法(CBT)与基于家庭的放松治疗(RT)对5至8岁患有强迫症(OCD)幼儿的相对疗效。
42名患有原发性强迫症的幼儿被随机分配接受12节基于家庭的CBT或基于家庭的RT治疗。由对治疗分配不知情的独立评估者在治疗前后进行评估。主要结局包括儿童耶鲁-布朗强迫症量表得分和临床总体印象改善情况。
对于意向性治疗样本,CBT具有中等治疗效果(d = 0.53),尽管在传统水平上两组之间没有显著差异。对于完成治疗样本,CBT有较大效果(d = 0.85),且存在显著的组间差异,CBT更具优势。在意向性治疗样本中,CBT组50%的儿童达到缓解,而RT组为20%。在完成治疗样本中,CBT组69%的儿童实现临床缓解,而RT组为20%。
结果表明,早发性强迫症儿童受益于根据其发育需求和家庭环境量身定制的治疗方法。CBT在减轻强迫症症状以及帮助大量儿童实现临床缓解方面有效。