Pritchard Verena E, Neumann Ewald, Rucklidge Julia J
Department of Psychology, University of Canterbury, Private Bag 4800, Christchurch, New Zealand.
Brain Cogn. 2008 Aug;67(3):324-39. doi: 10.1016/j.bandc.2008.02.002. Epub 2008 Mar 20.
Selective attention has durable consequences for behavior and neural activation. Negative priming (NP) effects are assumed to reflect a critical inhibitory component of selective attention. The performance of adolescents with Attention Deficit/Hyperactivity Disorder (ADHD) was assessed across two conceptually based NP tasks within a selective attention procedure. Comorbidity (non-comorbid ADHD vs. comorbid ADHD) and subtype (ADHD combined vs. ADHD inattentive) were considered key issues. Results found NP effects to differ as a function of comorbidity but not subtype. Findings are discussed in light of functional neuroimaging evidence for neuronal enhancement for unattended stimuli relative to attended stimuli that strongly complements an inhibitory-based explanation for NP. Implications for the 'AD' in ADHD and contemporary process models of the disorder are considered.
选择性注意对行为和神经激活具有持久影响。负启动（NP）效应被认为反映了选择性注意的一个关键抑制成分。在一个选择性注意程序中，通过两项基于概念的NP任务对患有注意力缺陷/多动障碍（ADHD）的青少年的表现进行了评估。共病情况（非共病ADHD与共病ADHD）和亚型（ADHD混合型与注意力不集中型ADHD）被视为关键问题。结果发现，NP效应因共病情况而异，而非因亚型而异。根据功能性神经影像学证据，即相对于被注意的刺激，未被注意的刺激的神经元增强，对研究结果进行了讨论，这一证据有力地补充了基于抑制的NP解释。文中还考虑了ADHD中“AD”的含义以及该疾病的当代过程模型。
