Zatoński Witold, Didkowska Joanna
Division of Epidemiology and Cancer Prevention Centre, Marie Sklodowska-Curie Memorial Cancer Centre, 5, Roentgen Str., 02-781 Warsaw, Poland.
Eur J Cancer. 2008 Jul;44(10):1425-37. doi: 10.1016/j.ejca.2008.02.014. Epub 2008 Mar 20.
The health transformation that took place after the Second World War in Europe was significantly delayed in the Central and Eastern European (CEE) countries compared to countries of Northern Europe and Great Britain. However, as death rates from cardiovascular disease have begun to fall, cancer has emerged, since the 1990s, as the most common cause of death among young and middle-aged adult women (20-64 years old) in these countries. In the coming decade it seems likely to be the leading cause of death among young and middle-aged adult men.
Data on deaths (1959-2002) in each country have been extracted from the World Health Organisation database. Population data are from the Population Division of the Department of Economic and Social Affairs of the United Nations. Direct standardisation has been undertaken using the World Standard Population.
The difference in life expectancy attributable to cancer for the 20-64 years of age group is 0.68 of a year (16% of the total gap) among men and 0.35 of a year (24% of the total) among women. Trends in cancer over time differ significantly by gender, age group and time period in Eastern and Western Europe. The predicted mortality rate in CEE in 2015 equates to 201/100,000 (95% CI 199-204) for men and 106/100,000 (95% CI 104-107) for women.
In CEE countries, deficiency of primary prevention is a main reason of poor health consciousness (consequences of smoking, fatty diet, low physical activity) and late introduction of secondary prevention responses results in worse survival of the cancer patient; however, tertiary prevention is implemented in a similar way as in western Europe. Our analysis indicates that the greatest possibilities, but also the greatest unmet needs, lie in primary and secondary prevention.
与北欧国家和英国相比,第二次世界大战后欧洲发生的健康转变在中东欧(CEE)国家显著延迟。然而,随着心血管疾病死亡率开始下降,自20世纪90年代以来,癌症已成为这些国家中青年成年女性(20 - 64岁)最常见的死亡原因。在未来十年,它似乎有可能成为中青年成年男性的主要死亡原因。
各国的死亡数据(1959 - 2002年)已从世界卫生组织数据库中提取。人口数据来自联合国经济和社会事务部人口司。已使用世界标准人口进行直接标准化。
20 - 64岁年龄组中,癌症导致的预期寿命差异在男性中为0.68年(占总差距的16%),在女性中为0.35年(占总数的24%)。东欧和西欧癌症随时间的趋势在性别、年龄组和时间段上有显著差异。预计2015年中东欧的死亡率男性为201/10万(95%可信区间199 - 204),女性为106/10万(95%可信区间104 - 107)。
在中东欧国家,一级预防不足是健康意识淡薄(吸烟、高脂肪饮食、缺乏体育活动的后果)的主要原因,二级预防措施引入较晚导致癌症患者生存率更低;然而,三级预防的实施方式与西欧类似。我们的分析表明,最大的可能性以及最大的未满足需求在于一级和二级预防。