Windebank Kevin P, Spinetta John J
Royal Victoria Infirmary, Newcastle upon Tyne, UK.
Pediatr Blood Cancer. 2008 May;50(5 Suppl):1099-100. doi: 10.1002/pbc.21460.
Adolescence is a time of great physical change and maturing brain function. This leads to adolescents establishing independence and coming to terms with the implications of their own actions. Not surprisingly, this phase is characterized by experimentation with both constructive and destructive behavior. Studies in many areas of chronic illness have shown that adolescents frequently neglect their care and revolt against the rules established during their childhood. It is therefore to be expected that teenagers diagnosed with a life threatening illness, such as cancer, may on occasion not fully comply with their therapy. The way forward includes improving communication and fully involving these young persons in their treatment planning, thereby moving from compliance to concordance. Additional improvements should be sought in medication, early recognition and support of familial or social problems, and using a specific adolescent multidisciplinary team. Research should not be limited to clinical trials.
青春期是身体发生巨大变化且大脑功能逐渐成熟的时期。这使得青少年开始建立独立性，并理解自身行为的影响。不足为奇的是，这个阶段的特点是既有建设性行为，也有破坏性行为的尝试。许多慢性病领域的研究表明，青少年常常忽视自身护理，反抗童年时期制定的规则。因此，可以预料，被诊断患有危及生命疾病（如癌症）的青少年有时可能不完全遵守治疗方案。前进的方向包括改善沟通，并让这些年轻人充分参与到治疗计划中，从而从依从转变为一致。还应在药物治疗、早期识别和支持家庭或社会问题以及组建专门的青少年多学科团队方面寻求更多改进。研究不应局限于临床试验。
