新生儿对上气道阻力增加的反应。
Response in the newborn to raised upper airway resistance.
作者信息
Purcell M
出版信息
Arch Dis Child. 1976 Aug;51(8):602-7. doi: 10.1136/adc.51.8.602.
Abstract
The effect of raising the airways resistance of 56 normal newborn babies by blocking alternate nostrils was studied by means of oesophageal intubation and the trunk plethysmograph. Increased resistance was associated with reduced respiratory rate and ventilation. A comparison was made of the response in different sleep states. In rapid eye movement (REM) sleep respiratory tidal volume decreased on blocking, there was no increase in the work of breathing and the fall in minute volume was greater than in non-REM sleep where tidal volume and minute work increased on blocking. These responses may be relevant to the sudden unexpected death syndrome in infancy, and to the management of normal newborns.
摘要
通过食管插管和体容积描记法研究了阻塞56名正常新生儿的交替鼻孔以增加气道阻力的效果。气道阻力增加与呼吸频率和通气量降低有关。对不同睡眠状态下的反应进行了比较。在快速眼动（REM）睡眠中，阻塞时呼吸潮气量减少，呼吸功没有增加，分钟通气量的下降幅度大于非快速眼动睡眠，在非快速眼动睡眠中，阻塞时潮气量和每分钟功增加。这些反应可能与婴儿猝死综合征以及正常新生儿的管理有关。
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